Protein: CRNN
Cornulin (53 kDa putative calcium-binding protein) (53 kDa squamous epithelial-induced stress protein) (58 kDa heat shock protein) (Squamous epithelial heat shock protein 53) (Tumor-related protein)

Gene: CRNN
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9UBG3

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0009408 - response to heat
GO:0010468 - regulation of gene expression
GO:0010838 - positive regulation of keratinocyte proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850910

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

3

3

High-throughput

0.667

High

1458396

UTP11
Probable U3 small nucleolar RNA-associated protein 11

3

1

High-throughput

0.667

High

1124113

RCAN2
Calcipressin-2

3

0

High-throughput

0.638

High

391668

FRIH
Ferritin heavy chain

2

2

High-throughput

0.628

High

1135396

SLMAP
Sarcolemmal membrane-associated protein

2

17

High-throughput

0.628

High

1449110

TNR19
Tumor necrosis factor receptor superfamily member 19

2

1

High-throughput

0.628

High

476201

ANXA5
Annexin A5

1

12

High-throughput

0.618

High

939021

UCP2
Dicarboxylate carrier SLC25A8

3

5

High-throughput

0.609

High

1394509

NSL1
Kinetochore-associated protein NSL1 homolog

3

2

High-throughput

0.609

High

1458389

GPN3
GPN-loop GTPase 3

3

1

High-throughput

0.609

High

1312827

NRM
Nurim

2

0

High-throughput

0.602

High

1337761

CA162
Transmembrane protein C1orf162

2

0

High-throughput

0.602

High

1458394

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.602

High

1245339

WDR59
GATOR2 complex protein WDR59

2

4

High-throughput

0.574

High

1276175

NUP54
Nucleoporin p54

2

1

High-throughput

0.574

High

1330866

FRMD1
FERM domain-containing protein 1

2

8

High-throughput

0.574

High

728457

AKT1
RAC-alpha serine/threonine-protein kinase

1

12

High-throughput

0.536

High

1044391

HSF2
Heat shock factor protein 2

1

5

High-throughput

0.536

High

1154466

STK11
Serine/threonine-protein kinase STK11

1

3

High-throughput

0.536

High

1323206

PDK1L
Serine/threonine-protein kinase PDIK1L

1

8

High-throughput

0.536

High

1328852

COMD1
COMM domain-containing protein 1

1

1

High-throughput

0.536

High

1351070

DDX54
ATP-dependent RNA helicase DDX54

1

4

High-throughput

0.536

High

1404993

GA2L1
GAS2-like protein 1

1

1

High-throughput

0.536

High

1412005

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.536

High

1417205

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.536

High

1458393

AURKC
Aurora kinase C

1

9

High-throughput

0.536

High

178993

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

911887

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.513

High

1394073

TM141
Transmembrane protein 141

1

0

High-throughput

0.513

High

1448870

SNX15
Sorting nexin-15

1

0

High-throughput

0.493

High

135836

RTCA
RNA 3'-terminal phosphate cyclase

1

1

High-throughput

0.489

High

608373

EGLN
Endoglin

1

1

High-throughput

0.489

High

622859

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

11

High-throughput

0.489

High

731668

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.489

High

913283

T2AG
Transcription initiation factor IIA subunit 2

1

1

High-throughput

0.489

High

1094526

ZN154
Zinc finger protein 154

1

4

High-throughput

0.489

High

1276070

ZN550
Zinc finger protein 550

1

9

High-throughput

0.489

High

1332810

FNDC5
Fibronectin type III domain-containing protein 5

1

7

High-throughput

0.489

High

1340015

O13C3
Olfactory receptor 13C3

1

1

High-throughput

0.489

High

1419203

PBX4
Pre-B-cell leukemia transcription factor 4

1

1

High-throughput

0.489

High

1437574

COE2
Transcription factor COE2

1

1

High-throughput

0.489

High

1458390

COR1C
Coronin-1C

1

2

High-throughput

0.489

High

376050

RASK
GTPase KRas

1

7

High-throughput

0.479

High

717628

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.479

High

877397

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.479

High

1270437

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

High-throughput

0.479

High

1458391

PA2G4
Proliferation-associated protein 2G4

1

1

High-throughput

0.479

High

1458392

CD11A
Cyclin-dependent kinase 11A

1

9

High-throughput

0.479

High

1418564

B3GN5
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase

1

5

High-throughput

0.470

High

258195

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

446473

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

957856

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

1090580

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1352806

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1453162

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1108242

SQSTM
Sequestosome-1

1

3

High-throughput

0.445

High

174629

TRI66
Tripartite motif-containing protein 66

1

19

High-throughput

0.437

High

1419519

NSD3
Histone-lysine N-methyltransferase NSD3

1

7

Small-scale

0.437

High

1458395

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

7

Small-scale

0.437

High

328453

SCEL
Sciellin

1

0

High-throughput

0.426

High

608004

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

0

High-throughput

0.426

High

1129282

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.426

High

1228375

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.426

High

554264

BMP4
Bone morphogenetic protein 4

1

3

High-throughput

0.407

High

1292352

ZC3C1
Zinc finger C3HC-type protein 1

1

3

High-throughput

0.407

High

1414731

RSRP1
Arginine/serine-rich protein 1

1

2

High-throughput

0.407

High

1248314

SFTA2
Surfactant-associated protein 2

2

0

High-throughput

0.328

High

1339904

NPB
Neuropeptide B

2

0

High-throughput

0.328

High

1349740

CMAP3
Ciliary microtubule-associated protein 3

2

0

High-throughput

0.318

High

965522

LMO4
LIM domain transcription factor LMO4

2

0

High-throughput

0.316

High

342685

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

868044

OMP
Olfactory marker protein

1

0

High-throughput

0.279

Low

967279

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

1111332

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1325489

FNBP4
Formin-binding protein 4

1

0

High-throughput

0.279

Low

1327668

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.279

Low

1413453

DCTN5
Dynactin subunit 5

1

0

High-throughput

0.279

Low

1435021

TM231
Transmembrane protein 231

1

0

High-throughput

0.279

Low

1446300

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.279

Low

939481

RAG2
V(D)J recombination-activating protein 2

1

0

High-throughput

0.269

Low

471942

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.249

Low

883350

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

769796

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.232

Low

1458388

DYH17
Dynein axonemal heavy chain 17

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025