HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 651
+	Hs
		370499 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		370458 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		BRD9_HUMAN (1-590): 1.05e-85: 282: 32.61
+	Hs
		876710 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		998934 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1269276 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1269570 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		369484 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		370136 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Mm
		101423 ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72		F8VPR5_MOUSE (25-251): 6.54e-42: 166: 22.27
+	Mm
		70893 ESR1_MOUSE (9-529): 4.88e-134: 403: 43.72		EP300_MOUSE (42-238): 3.03e-40: 160: 22.93
+	Hs
		1017331 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Hs
		369011 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		510043 ERR1_HUMAN (85-497): 1.88e-112: 342: 35.65		BRPF3_HUMAN (3-537): 1.76e-54: 203: 16.33
+	Hs
		370401 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		587157 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Mm
		101427 RXRG_MOUSE (13-499): 5.3e-117: 355: 22.56		F8VPR5_MOUSE (25-251): 6.54e-42: 166: 22.27
+	Hs
		587190 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		370655 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		BAZ2A_HUMAN (70-240): 3.27e-19: 94.9: 22.65
+	Mm
		70894 RARB_MOUSE (30-529): 3.81e-112: 343: 23.81		EP300_MOUSE (42-238): 3.03e-40: 160: 22.93
+	Hs
		587198 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23