Protein: PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (EC 2.3.1.23) (EC 2.3.1.51) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Sphingolipid compensation protein 1)

Gene: PLSC, SLC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P33333

Gene Ontology (top 5):
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005811 - lipid droplet
GO:0005886 - plasma membrane
GO:0006654 - phosphatidic acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704615

GCN1
eIF-2-alpha kinase activator GCN1

3

2

High-throughput

0.587

High

704629

IMB4
Importin subunit beta-4

3

4

High-throughput

0.587

High

704619

GPT2
Glycerol-3-phosphate O-acyltransferase 2

2

1

Small-scale

0.586

High

704622

FAT1
Very long-chain fatty acid transport protein

1

1

High-throughput

0.541

High

704632

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

3

High-throughput

0.541

High

502974

SEC7
Protein transport protein SEC7

2

1

High-throughput

0.537

High

704625

ECM29
Proteasome component ECM29

2

4

High-throughput

0.537

High

495812

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.518

High

657787

MGLL
Monoglyceride lipase

1

0

High-throughput

0.518

High

704616

RER2
Dehydrodolichyl diphosphate synthase complex subunit RER2

1

0

High-throughput

0.518

High

704624

ERG7
Lanosterol synthase ERG7

1

0

High-throughput

0.518

High

697787

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

Small-scale

0.481

High

543473

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

689068

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

Small-scale

0.479

High

704631

ELO3
Fatty acid elongase 3

1

3

High-throughput

0.479

High

704640

ERV14
ER-derived vesicles protein ERV14

1

1

High-throughput

0.479

High

704649

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

2

High-throughput

0.479

High

596961

ACO1
Acyl-CoA desaturase 1

1

0

Small-scale

0.460

High

704647

DGAT2
Diacylglycerol O-acyltransferase 1

1

0

Small-scale

0.460

High

520242

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.458

High

629461

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

0

High-throughput

0.458

High

701642

SRPR
Signal recognition particle receptor subunit alpha homolog

1

0

High-throughput

0.458

High

704614

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

704618

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

704623

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

704627

NSG1
Protein NSG1

1

0

High-throughput

0.458

High

704633

LCB2
Serine palmitoyltransferase 2

1

0

High-throughput

0.458

High

493572

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

510770

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

560617

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.445

High

704626

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.445

High

675922

XPO1
Exportin-1

1

1

High-throughput

0.437

High

687915

IMB3
Importin subunit beta-3

1

5

High-throughput

0.437

High

704620

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

704621

IMB2
Importin subunit beta-2

1

4

High-throughput

0.437

High

704643

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

704644

SXM1
Importin beta SMX1

1

1

High-throughput

0.437

High

704646

IMB1
Importin subunit beta-1

1

4

High-throughput

0.437

High

340092

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

421609

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

415934

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.407

High

498865

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

693272

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.407

High

700313

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.407

High

703872

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.407

High

704639

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.407

High

568301

CAP
Adenylyl cyclase-associated protein

2

0

High-throughput

0.307

High

581347

MED14
Mediator of RNA polymerase II transcription subunit 14

2

0

High-throughput

0.307

High

704628

TCPD
T-complex protein 1 subunit delta

2

0

High-throughput

0.307

High

704635

GCN20
Protein GCN20

2

0

High-throughput

0.307

High

680582

HS104
Heat shock protein 104

2

0

High-throughput

0.305

High

536674

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

704617

KES1
Oxysterol-binding protein homolog 4

1

0

High-throughput

0.282

High

704648

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.282

High

539969

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.279

Low

619661

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.279

Low

704645

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

357242

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

661786

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

704636

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

704637

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

704638

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

704641

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

704642

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.249

Low

367913

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

376707

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

399395

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

404538

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

424438

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

534932

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.232

Low

645347

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low

704630

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.232

Low

704634

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024