Protein: MSH2
DNA mismatch repair protein MSH2 (MutS protein homolog 2)

Gene: MSH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P25847

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000400 - four-way junction DNA binding
GO:0000406 - double-strand/single-strand DNA junction binding
GO:0000710 - meiotic mismatch repair
GO:0000735 - removal of nonhomologous ends

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

639287

MSH6
DNA mismatch repair protein MSH6

33

13

Small-scale

0.993

High

629321

MSH3
DNA mismatch repair protein MSH3

10

12

Small-scale

0.975

High

639267

MLH1
DNA mismatch repair protein MLH1

7

20

Small-scale

0.963

High

536213

PMS1
DNA mismatch repair protein PMS1

7

20

Small-scale

0.963

High

543297

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.759

High

639270

EXO1
Exodeoxyribonuclease 1

7

6

Small-scale

0.748

High

550522

PCNA
Proliferating cell nuclear antigen

7

9

Small-scale

0.741

High

639269

SAW1
Single-strand annealing weakened protein 1

3

1

Small-scale

0.680

High

607214

RFA1
Replication factor A protein 1

3

5

Small-scale

0.662

High

420435

RAD10
DNA repair protein RAD10

2

2

Small-scale

0.651

High

639294

MLH2
DNA mismatch repair protein MLH2

1

20

Small-scale

0.647

High

639292

HDA2
HDA1 complex subunit 2

3

0

High-throughput

0.637

High

419531

RAD1
DNA repair protein RAD1

2

2

Small-scale

0.605

High

639280

PROA
Gamma-glutamyl phosphate reductase

2

0

High-throughput

0.595

High

639291

HDA3
HDA1 complex subunit 3

2

0

High-throughput

0.595

High

485664

IF4A
ATP-dependent RNA helicase eIF4A

2

1

High-throughput

0.588

High

639276

RSC8
Chromatin structure-remodeling complex protein RSC8

2

1

High-throughput

0.588

High

639250

RAD14
DNA repair protein RAD14

1

2

Small-scale

0.573

High

639285

LGE1
Transcriptional regulatory protein LGE1

2

2

High-throughput

0.571

High

639288

RUVB1
RuvB-like protein 1

2

1

High-throughput

0.571

High

639279

HDA1
Histone deacetylase HDA1

2

3

High-throughput

0.567

High

639266

OLA1
Obg-like ATPase 1

2

0

High-throughput

0.563

High

425543

RAD2
DNA repair protein RAD2

1

6

Small-scale

0.552

High

639297

SLX4
Structure-specific endonuclease subunit SLX4

1

1

Small-scale

0.552

High

493334

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

510445

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.552

High

639282

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

0

Small-scale

0.549

High

639290

SWR1
Helicase SWR1

1

2

High-throughput

0.541

High

639286

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.518

High

604293

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

639262

SGS1
ATP-dependent helicase SGS1

1

8

Small-scale

0.501

High

639249

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.493

High

639271

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.493

High

639273

MMM1
Maintenance of mitochondrial morphology protein 1

1

2

Small-scale

0.489

High

420473

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.486

High

639252

FUN30
ATP-dependent helicase FUN30

1

7

Small-scale

0.481

High

639260

RAD5
DNA repair protein RAD5

1

8

Small-scale

0.481

High

639275

GZF3
Protein GZF3

1

2

High-throughput

0.481

High

639283

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.481

High

557913

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

639251

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

639253

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

639258

MG101
Mitochondrial genome maintenance protein MGM101

1

1

Small-scale

0.479

High

639259

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

639272

MPH1
ATP-dependent DNA helicase MPH1

1

3

High-throughput

0.479

High

639281

H3
Histone H3

1

10

High-throughput

0.479

High

639296

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

639299

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.479

High

608448

SAN1
Protein SAN1

1

0

Small-scale

0.460

High

639248

DPB3
DNA polymerase epsilon subunit C

1

0

Small-scale

0.460

High

639261

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

639295

SGO1
Shugoshin

1

0

High-throughput

0.458

High

639284

UBC7
Ubiquitin-conjugating enzyme E2 7

1

4

High-throughput

0.457

High

340045

KPYK1
Pyruvate kinase 1

1

3

High-throughput

0.445

High

392321

H2A2
Histone H2A.2

1

4

High-throughput

0.445

High

490496

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

555852

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

625904

ROX1
Repressor ROX1

1

2

High-throughput

0.445

High

632983

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

639255

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

639257

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

639264

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

639289

YHP1
Homeobox protein YHP1

1

1

High-throughput

0.445

High

639298

RLF2
Chromatin assembly factor 1 subunit p90

1

5

High-throughput

0.445

High

639254

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

2

High-throughput

0.437

High

639263

UTP20
U3 small nucleolar RNA-associated protein 20

1

1

High-throughput

0.437

High

454208

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

639256

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

367794

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.407

High

639274

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.407

High

639278

TPC1
Mitochondrial thiamine pyrophosphate carrier 1

1

0

High-throughput

0.282

High

639265

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

639268

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

639293

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

474394

YL016
Putative truncated guanine nucleotide exchange factor SDC25

1

0

High-throughput

0.238

Low

639277

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024