HitPredict - High confidence protein-protein interactions

Protein: AK1H
Bifunctional aspartokinase/homoserine dehydrogenase 1 (Aspartokinase I/homoserine dehydrogenase I) (AKI-HDI) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]

Gene: AK1H, thrA
Organism: Escherichia coli K-12
Interactions: 7
UniProt ID: P00561

Gene Ontology (top 5):
GO:0004072 - aspartate kinase activity
GO:0004412 - homoserine dehydrogenase activity
GO:0005524 - ATP binding
GO:0009086 - methionine biosynthetic process
GO:0009088 - threonine biosynthetic process

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
365720	HSLU ATP-dependent protease ATPase subunit HslU	2	1	High-throughput	0.611	High
365723	DNAB Replicative DNA helicase DnaB	2	0	High-throughput	0.585	High
365722	G6PD Glucose-6-phosphate 1-dehydrogenase	1	0	High-throughput	0.513	High
365724	GLPD Aerobic glycerol-3-phosphate dehydrogenase	1	0	High-throughput	0.279	Low
365725	AHPF Alkyl hydroperoxide reductase subunit F	1	0	High-throughput	0.279	Low
365726	CSPB Cold shock-like protein CspB	1	0	High-throughput	0.279	Low
365721	TIG Trigger factor	1	0	Small-scale	0.232	Low

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Last updated: 11Aug2025