Protein: HSLU
ATP-dependent protease ATPase subunit HslU (Heat shock protein HslU) (Unfoldase HslU)

Gene: HSLU
Organism: Escherichia coli K-12
Interactions: 49
UniProt ID: P0A6H5

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

490322

HSLV
ATP-dependent protease subunit HslV

8

0

Small-scale

0.916

High

490318

HSLU
ATP-dependent protease ATPase subunit HslU

4

2

Small-scale

0.882

High

490333

LON
Lon protease

1

2

High-throughput

0.625

High

365720

AK1H
Bifunctional aspartokinase/homoserine dehydrogenase 1

2

1

High-throughput

0.611

High

490347

EFTU1
Elongation factor Tu 1

2

5

High-throughput

0.611

High

490319

EFG
Elongation factor G

2

2

High-throughput

0.588

High

490323

RECA
Protein RecA

2

1

High-throughput

0.588

High

490329

METK
S-adenosylmethionine synthase

2

1

High-throughput

0.588

High

490335

MREB
Cell shape-determining protein MreB

2

4

High-throughput

0.588

High

490344

MGLB
D-galactose/methyl-galactoside binding periplasmic protein MglB

2

2

High-throughput

0.588

High

490352

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

2

0

High-throughput

0.585

High

490339

BCCP
Biotin carboxyl carrier protein of acetyl-CoA carboxylase

2

0

High-throughput

0.563

High

473238

DNAJ
Chaperone protein DnaJ

1

1

High-throughput

0.561

High

490357

YDEN
Uncharacterized sulfatase YdeN

2

1

High-throughput

0.558

High

490328

RS5
Small ribosomal subunit protein uS5

1

1

High-throughput

0.536

High

490354

NUOCD
NADH-quinone oxidoreductase subunit C/D

1

1

High-throughput

0.536

High

382622

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

449896

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

1

0

High-throughput

0.513

High

479533

NARG
Respiratory nitrate reductase 1 alpha chain

1

0

High-throughput

0.513

High

490343

CYSW
Sulfate transport system permease protein CysW

1

0

High-throughput

0.513

High

490349

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.513

High

490350

ACCC
Biotin carboxylase

1

0

High-throughput

0.513

High

490355

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

490320

DNAK
Chaperone protein DnaK

1

4

High-throughput

0.484

High

490325

RL7
Large ribosomal subunit protein bL12

1

1

High-throughput

0.484

High

490338

PSTB
Phosphate import ATP-binding protein PstB

1

1

High-throughput

0.484

High

490324

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.464

High

490326

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.464

High

490334

ACCD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

1

0

High-throughput

0.464

High

490336

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

490356

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

490348

EFTU2
Elongation factor Tu 2

1

5

High-throughput

0.457

High

490332

FTSZ
Cell division protein FtsZ

1

1

High-throughput

0.442

High

490337

THIO
Thioredoxin 1

1

0

Small-scale

0.426

High

490345

SULA
Cell division inhibitor SulA

3

0

Small-scale

0.345

High

490351

RIBD
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase

2

0

High-throughput

0.318

High

490359

YDGA
Protein YdgA

2

0

High-throughput

0.318

High

490330

ARGP
HTH-type transcriptional regulator ArgP

2

0

High-throughput

0.307

High

490331

OMPX
Outer membrane protein X

2

0

High-throughput

0.307

High

490346

GATZ
D-tagatose-1,6-bisphosphate aldolase subunit GatZ

2

0

High-throughput

0.307

High

490321

GPMB
Probable phosphoglycerate mutase GpmB

1

0

High-throughput

0.279

Low

490327

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

490340

CYOA
Cytochrome bo(3) ubiquinol oxidase subunit 2

1

0

High-throughput

0.279

Low

490353

FTSP
Cell division protein FtsP

1

0

High-throughput

0.279

Low

490358

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

0

High-throughput

0.279

Low

490360

YGEG
Uncharacterized protein YgeG

1

0

High-throughput

0.279

Low

490341

CCMB
Heme exporter protein B

1

0

High-throughput

0.253

Low

490342

RL16
Large ribosomal subunit protein uL16

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025