Protein: UME6
Transcriptional regulatory protein UME6 (Negative transcriptional regulator of IME2) (Regulator of inducer of meiosis protein 16) (Unscheduled meiotic gene expression protein 6)

Gene: UME6
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P39001

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001081 - nitrogen catabolite repression of transcription from RNA polymerase II promoter
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597109

IME1
Meiosis-inducing protein 1

8

0

Small-scale

0.709

High

750927

RIM11
Serine/threonine-protein kinase RIM11/MSD1

4

1

Small-scale

0.707

High

693015

RPD3
Histone deacetylase RPD3

6

0

Small-scale

0.697

High

609087

SIN3
Transcriptional regulatory protein SIN3

5

0

Small-scale

0.688

High

758982

RXT3
Transcriptional regulatory protein RXT3

4

0

Small-scale

0.661

High

758969

SDS3
Transcriptional regulatory protein SDS3

3

0

Small-scale

0.622

High

396179

ARGR2
Arginine metabolism regulation protein II

1

0

Small-scale

0.622

High

747149

RXT2
Transcriptional regulatory protein RXT2

3

0

Small-scale

0.606

High

758973

TEA1
TY1 enhancer activator

1

0

Small-scale

0.589

High

758967

UME6
Transcriptional regulatory protein UME6

1

0

Small-scale

0.586

High

758984

CTI6
Histone deacetylase complex subunit CTI6

2

0

Small-scale

0.585

High

758977

GCN5
Histone acetyltransferase GCN5

2

0

Small-scale

0.577

High

640839

CDC20
APC/C activator protein CDC20

1

0

Small-scale

0.537

High

758983

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

0

Small-scale

0.537

High

511324

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

602676

MCK1
Protein kinase MCK1

1

1

Small-scale

0.508

High

392430

H2A2
Histone H2A.2

1

0

High-throughput

0.493

High

758981

PBP4
Protein PBP4

1

0

High-throughput

0.493

High

758985

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

614500

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

1

Small-scale

0.489

High

423714

ARGR1
Arginine metabolism regulation protein I

1

0

Small-scale

0.486

High

758970

GLDS1
Protein GDS1

1

0

High-throughput

0.486

High

412751

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

542124

CYC8
General transcriptional corepressor CYC8

1

0

Small-scale

0.480

High

561872

TUP1
General transcriptional corepressor TUP1

1

0

Small-scale

0.480

High

623824

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.480

High

758972

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

355484

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

355894

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

356477

H4
Histone H4

1

0

High-throughput

0.458

High

558057

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

662231

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

680083

DEP1
Transcriptional regulatory protein DEP1

1

0

Small-scale

0.458

High

710734

ASH1
Transcriptional regulatory protein ASH1

1

0

Small-scale

0.458

High

716238

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

750101

SAP30
Transcriptional regulatory protein SAP30

1

0

Small-scale

0.458

High

758974

PHO23
Transcriptional regulatory protein PHO23

1

0

Small-scale

0.458

High

758975

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.458

High

758976

UME1
Transcriptional regulatory protein UME1

1

0

Small-scale

0.458

High

758979

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

758986

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

540230

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

1

Small-scale

0.457

High

491234

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493977

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

694708

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

743535

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

715890

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.265

Low

543740

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

700738

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.249

Low

758978

RMD1
Sporulation protein RMD1

1

0

High-throughput

0.238

Low

758968

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

758971

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

758980

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024