Protein: ATP6
ATP synthase subunit a (F-ATPase protein 6)

Gene: ATP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P00854

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0015078 - proton transmembrane transporter activity
GO:0015986 - proton motive force-driven ATP synthesis
GO:0045259 - proton-transporting ATP synthase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

367203

ATPF
ATP synthase subunit 4, mitochondrial

5

0

Small-scale

0.871

High

367230

ATP7
ATP synthase subunit d, mitochondrial

4

0

Small-scale

0.833

High

367260

ATP18
ATP synthase subunit J, mitochondrial

4

0

Small-scale

0.833

High

367196

ATP8
ATP synthase protein 8

4

0

Small-scale

0.823

High

367257

ATP9
ATP synthase subunit 9, mitochondrial

3

1

Small-scale

0.817

High

366856

ATPB
ATP synthase subunit beta, mitochondrial

7

1

Small-scale

0.729

High

367272

ATPK
ATP synthase subunit f, mitochondrial

2

0

Small-scale

0.728

High

367261

ATP19
ATP synthase subunit K, mitochondrial

2

0

Small-scale

0.716

High

367206

ATPA
ATP synthase subunit alpha, mitochondrial

5

1

Small-scale

0.702

High

367221

ATP10
Mitochondrial ATPase complex subunit ATP10

3

0

Small-scale

0.613

High

367224

ATP5E
ATP synthase subunit epsilon, mitochondrial

3

0

Small-scale

0.613

High

367275

ATPD
ATP synthase subunit delta, mitochondrial

3

0

Small-scale

0.613

High

367279

ATP14
ATP synthase subunit H, mitochondrial

3

0

Small-scale

0.613

High

367291

YO020
Uncharacterized protein YOR020W-A

1

0

Small-scale

0.586

High

367237

ATPG
ATP synthase subunit gamma, mitochondrial

2

1

Small-scale

0.584

High

360737

COX3
Cytochrome c oxidase subunit 3

2

0

Small-scale

0.569

High

367210

ATPO
ATP synthase subunit 5, mitochondrial

2

0

Small-scale

0.569

High

367197

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

2

0

Small-scale

0.559

High

367231

MSS51
Protein MSS51, mitochondrial

2

0

Small-scale

0.559

High

367244

COX14
Cytochrome c oxidase assembly protein COX14

2

0

Small-scale

0.559

High

367245

OXA1
Mitochondrial inner membrane protein OXA1

2

0

Small-scale

0.559

High

367277

ATPN
ATP synthase subunit g, mitochondrial

2

0

Small-scale

0.559

High

267933

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

Small-scale

0.458

High

357681

CYC1
Cytochrome c isoform 1

1

0

Small-scale

0.458

High

357794

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

0

Small-scale

0.458

High

360307

COX1
Cytochrome c oxidase subunit 1

1

0

Small-scale

0.458

High

360761

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

Small-scale

0.458

High

360844

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

0

Small-scale

0.458

High

367200

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

Small-scale

0.458

High

367201

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

Small-scale

0.458

High

367207

COX9
Cytochrome c oxidase subunit 9, mitochondrial

1

0

Small-scale

0.458

High

367209

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

Small-scale

0.458

High

367212

YG41A
Uncharacterized protein YGL041W-A, mitochondrial

1

0

Small-scale

0.458

High

367214

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

367217

RS18A
Small ribosomal subunit protein uS13A

1

0

Small-scale

0.458

High

367218

COX7
Cytochrome c oxidase subunit 7, mitochondrial

1

0

Small-scale

0.458

High

367220

GLRX2
Glutaredoxin-2

1

0

Small-scale

0.458

High

367222

RM44
Large ribosomal subunit protein mL53

1

0

Small-scale

0.458

High

367223

RM33
Large ribosomal subunit protein uL30m

1

0

Small-scale

0.458

High

367226

TRX1
Thioredoxin-1

1

0

Small-scale

0.458

High

367227

QCR9
Cytochrome b-c1 complex subunit 9, mitochondrial

1

0

Small-scale

0.458

High

367228

RM25
Large ribosomal subunit protein mL59

1

0

Small-scale

0.458

High

367233

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

Small-scale

0.458

High

367236

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

Small-scale

0.458

High

367238

OM14
Mitochondrial outer membrane protein OM14

1

0

Small-scale

0.458

High

367239

MIC12
MICOS complex subunit MIC12

1

0

Small-scale

0.458

High

367242

CH10
10 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

367243

PT100
Protein PET100, mitochondrial

1

0

Small-scale

0.458

High

367247

INA22
Inner membrane assembly complex subunit 22

1

0

High-throughput

0.458

High

367251

TOM22
Mitochondrial import receptor subunit TOM22

1

0

Small-scale

0.458

High

367254

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

367255

RM50
Large ribosomal subunit protein bL9m

1

0

Small-scale

0.458

High

367259

ATPJ
ATP synthase subunit e, mitochondrial

1

0

Small-scale

0.458

High

367262

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

0

Small-scale

0.458

High

367264

PT117
Protein PET117, mitochondrial

1

0

Small-scale

0.458

High

367265

ISU1
Iron sulfur cluster assembly protein 1, mitochondrial

1

0

Small-scale

0.458

High

367266

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

Small-scale

0.458

High

367269

SDHF3
Succinate dehydrogenase assembly factor 3, mitochondrial

1

0

Small-scale

0.458

High

367270

RM34
Large ribosomal subunit protein bL34m

1

0

Small-scale

0.458

High

367271

ECM19
Protein ECM19

1

0

Small-scale

0.458

High

367273

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

Small-scale

0.458

High

367274

YD157
Uncharacterized protein YDL157C, mitochondrial

1

0

Small-scale

0.458

High

367276

NCE2
Non-classical export protein 2

1

0

Small-scale

0.458

High

367278

RDL1
Thiosulfate:glutathione sulfurtransferase

1

0

Small-scale

0.458

High

367280

RM23
Large ribosomal subunit protein uL13m

1

0

Small-scale

0.458

High

367283

COX26
Cytochrome c oxidase subunit 26, mitochondrial

1

0

Small-scale

0.458

High

367284

YD381
Uncharacterized mitochondrial outer membrane protein YDR381C-A

1

0

Small-scale

0.458

High

367286

SDHF1
Succinate dehydrogenase assembly factor 1, mitochondrial

1

0

Small-scale

0.458

High

367287

BOL1
BolA-like protein 1

1

0

Small-scale

0.458

High

367289

COXM2
COX assembly mitochondrial protein 2

1

0

Small-scale

0.458

High

367290

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

1

0

Small-scale

0.458

High

367293

ISD11
Protein ISD11

1

0

Small-scale

0.458

High

367294

MIC10
MICOS complex subunit MIC10

1

0

Small-scale

0.458

High

367252

SC6B1
Protein transport protein SBH1

1

1

Small-scale

0.437

High

367253

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.437

High

367281

H2AZ
Histone H2A.Z

1

1

Small-scale

0.437

High

367229

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.265

Low

64206

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

367198

H2B2
Histone H2B.2

1

0

Small-scale

0.249

Low

367199

H4
Histone H4

1

0

Small-scale

0.249

Low

367202

H2A2
Histone H2A.2

1

0

Small-scale

0.249

Low

367204

RL36A
Large ribosomal subunit protein eL36A

1

0

Small-scale

0.249

Low

367205

RS14A
Small ribosomal subunit protein uS11A

1

0

Small-scale

0.249

Low

367208

RS19A
Small ribosomal subunit protein eS19A

1

0

Small-scale

0.249

Low

367211

RS22A
Small ribosomal subunit protein uS8A

1

0

Small-scale

0.249

Low

367213

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

0

Small-scale

0.249

Low

367215

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.249

Low

367216

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.249

Low

367219

RL30
Large ribosomal subunit protein eL30

1

0

Small-scale

0.249

Low

367225

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

367232

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

367234

SNC2
Synaptobrevin homolog 2

1

0

Small-scale

0.249

Low

367235

SC61G
Protein transport protein SSS1

1

0

Small-scale

0.249

Low

367240

YSY6
Protein YSY6

1

0

Small-scale

0.249

Low

367241

RS27B
Small ribosomal subunit protein eS27B

1

0

Small-scale

0.249

Low

367246

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

Small-scale

0.249

Low

367248

RS29A
Small ribosomal subunit protein uS14A

1

0

Small-scale

0.249

Low

367249

RS10B
Small ribosomal subunit protein eS10B

1

0

Small-scale

0.249

Low

367250

RL38
Large ribosomal subunit protein eL38

1

0

Small-scale

0.249

Low

367256

PGA2
Processing of GAS1 and ALP protein 2

1

0

Small-scale

0.249

Low

367258

H3
Histone H3

1

0

Small-scale

0.249

Low

367263

RS15
Small ribosomal subunit protein uS19

1

0

Small-scale

0.249

Low

367267

PKR1
V-type ATPase assembly factor PKR1

1

0

Small-scale

0.249

Low

367268

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

367282

YK023
Uncharacterized protein YKL023C-A

1

0

Small-scale

0.249

Low

367285

YI021
Uncharacterized protein YIR021W-A

1

0

Small-scale

0.249

Low

367288

YL361
Uncharacterized protein YLR361C-A

1

0

Small-scale

0.249

Low

367292

YOS1
Protein transport protein YOS1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025