Protein: ORC4
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)

Gene: ORC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P54791

Gene Ontology (top 5):
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005664 - nuclear origin of replication recognition complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

872780

ORC1
Origin recognition complex subunit 1

17

15

Small-scale

0.986

High

842058

ORC5
Origin recognition complex subunit 5

11

13

Small-scale

0.980

High

698732

ORC2
Origin recognition complex subunit 2

10

13

Small-scale

0.972

High

447807

CDC6
Cell division control protein 6

5

16

Small-scale

0.912

High

872887

ORC3
Origin recognition complex subunit 3

8

2

Small-scale

0.747

High

667615

MCM2
DNA replication licensing factor MCM2

1

19

Small-scale

0.734

High

755750

ORC6
Origin recognition complex subunit 6

6

2

Small-scale

0.727

High

744587

PCH2
Pachytene checkpoint protein 2

1

1

Small-scale

0.647

High

673215

CGS5
S-phase entry cyclin-5

2

9

Small-scale

0.611

High

355970

H2B2
Histone H2B.2

2

5

High-throughput

0.601

High

765954

HAT2
Histone acetyltransferase type B subunit 2

2

2

Small-scale

0.601

High

872903

HAT1
Histone acetyltransferase type B catalytic subunit

2

1

Small-scale

0.601

High

744786

MCM7
DNA replication licensing factor MCM7

1

18

Small-scale

0.575

High

772312

ATAD2
ATPase histone chaperone YTA7

1

1

High-throughput

0.575

High

859000

MCM6
DNA replication licensing factor MCM6

1

20

Small-scale

0.575

High

355586

H2B1
Histone H2B.1

2

5

High-throughput

0.571

High

356648

H4
Histone H4

2

5

High-throughput

0.571

High

866400

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.552

High

769161

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

695287

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.536

High

622886

DPB2
DNA polymerase epsilon subunit B

1

1

High-throughput

0.515

High

872901

YRA1
RNA annealing protein YRA1

1

2

High-throughput

0.515

High

705516

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.514

High

688660

MCM10
Minichromosome maintenance protein 10

1

4

Small-scale

0.501

High

693739

IME2
Meiosis induction protein kinase IME2/SME1

1

13

Small-scale

0.501

High

811836

CDT1
Cell division cycle protein CDT1

1

2

Small-scale

0.501

High

392530

H2A2
Histone H2A.2

1

3

High-throughput

0.479

High

663016

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

698902

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

716315

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

774189

FKH1
Fork head protein homolog 1

1

4

Small-scale

0.479

High

872896

ORC4
Origin recognition complex subunit 4

1

14

Small-scale

0.479

High

872898

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

872899

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

872900

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

743634

HMT1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.457

High

492104

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

494689

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

512330

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

689930

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.445

High

733283

SET3
SET domain-containing protein 3

1

2

High-throughput

0.445

High

872904

RLF2
Chromatin assembly factor 1 subunit p90

1

1

High-throughput

0.445

High

770098

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

872897

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

872902

HSP42
Heat shock protein 42

1

3

High-throughput

0.407

High

810101

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024