Protein: DAM1
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)

Gene: DAM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P53267

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

859844

DUO1
DASH complex subunit DUO1

14

0

Small-scale

0.933

High

860966

DAD1
DASH complex subunit DAD1

11

0

Small-scale

0.929

High

733414

SPC34
DASH complex subunit SPC34

12

0

Small-scale

0.928

High

860959

SPC19
DASH complex subunit SPC19

6

0

Small-scale

0.896

High

734075

DAD2
DASH complex subunit DAD2

4

0

Small-scale

0.845

High

758801

IPL1
Spindle assembly checkpoint kinase

7

1

Small-scale

0.749

High

774062

NDC80
Kinetochore protein NDC80

11

0

Small-scale

0.725

High

728368

ASK1
DASH complex subunit ASK1

7

0

Small-scale

0.707

High

775794

DSN1
Kinetochore-associated protein DSN1

7

0

Small-scale

0.707

High

860949

DAM1
DASH complex subunit DAM1

4

0

Small-scale

0.669

High

860956

HSK3
DASH complex subunit HSK3

5

0

Small-scale

0.667

High

860955

DAD4
DASH complex subunit DAD4

4

0

Small-scale

0.653

High

747746

SLI15
Inner centromere protein-related protein SLI15

3

0

Small-scale

0.639

High

860962

ATG17
Autophagy-related protein 17

3

0

Small-scale

0.630

High

766764

BIM1
Protein BIM1

2

0

Small-scale

0.616

High

860954

DAD3
DASH complex subunit DAD3

3

0

Small-scale

0.614

High

860957

CENPP
Inner kinetochore subunit CTF19

2

0

Small-scale

0.583

High

860963

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.582

High

708034

NUF2
Kinetochore protein NUF2

2

0

Small-scale

0.577

High

687976

IMB3
Importin subunit beta-3

2

0

Small-scale

0.576

High

860967

CENPH
Inner kinetochore subunit MCM16

2

0

Small-scale

0.565

High

805155

STU2
Protein STU2

2

0

Small-scale

0.551

High

860950

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.518

High

691918

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

Small-scale

0.513

High

860951

CENPQ
Inner kinetochore subunit OKP1

1

0

Small-scale

0.513

High

811277

MAD3
Spindle assembly checkpoint component MAD3

1

1

Small-scale

0.479

High

748293

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.458

High

757224

CENPN
Inner kinetochore subunit CHL4

1

0

Small-scale

0.458

High

778466

MAD1
Spindle assembly checkpoint component MAD1

1

0

Small-scale

0.458

High

798056

CENPT
Inner kinetochore subunit CNN1

1

0

Small-scale

0.458

High

812271

BIR1
Protein BIR1

1

0

Small-scale

0.458

High

812574

CENPK
Inner kinetochore subunit MCM22

1

0

Small-scale

0.458

High

860958

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

860961

SPC24
Kinetochore protein SPC24

1

0

Small-scale

0.458

High

550086

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.457

High

584770

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.457

High

629749

STE50
Protein STE50

1

0

Small-scale

0.438

High

664960

BMH1
Protein BMH1

1

0

Small-scale

0.438

High

691235

MKK2
MAP kinase kinase MKK2/SSP33

1

0

Small-scale

0.438

High

746226

SHE1
Mitotic spindle-associated protein SHE1

1

0

Small-scale

0.438

High

783881

BUD6
Bud site selection protein 6

1

0

Small-scale

0.438

High

860964

ADY3
Accumulates dyads protein 3

1

0

Small-scale

0.438

High

860968

NOT5
General negative regulator of transcription subunit 5

1

0

Small-scale

0.438

High

783851

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

2

Small-scale

0.437

High

494543

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

747521

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

860953

MPS1
Serine/threonine-protein kinase MPS1

4

0

Small-scale

0.357

High

730865

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.320

High

859717

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

2

0

Small-scale

0.317

High

778688

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.282

High

811065

SNX4
Sorting nexin-4

1

0

Small-scale

0.282

High

716134

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

Small-scale

0.279

Low

755787

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

Small-scale

0.269

Low

413004

KAPB
cAMP-dependent protein kinase type 2

1

0

Small-scale

0.261

Low

565162

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.261

Low

355566

H2B1
Histone H2B.1

1

0

Small-scale

0.249

Low

392165

H2A1
Histone H2A.1

1

0

Small-scale

0.249

Low

662868

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

778658

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.249

Low

768094

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

Small-scale

0.238

Low

768337

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

Small-scale

0.238

Low

772777

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.238

Low

814165

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

Small-scale

0.238

Low

837239

KEL2
Kelch repeat-containing protein 2

1

0

Small-scale

0.238

Low

860952

SPO1
Putative meiotic phospholipase SPO1

1

0

Small-scale

0.238

Low

860960

ECM11
Protein ECM11

1

0

Small-scale

0.238

Low

860965

YAP7
AP-1-like transcription factor YAP7

1

0

Small-scale

0.238

Low

760914

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

860969

CENPW
Inner kinetochore subunit WIP1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024