Protein: HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial (EC 3.6.4.10) (Heat shock protein SSQ1, mitochondrial) (Stress-seventy subfamily Q protein 1) (mtHSP70 homolog)

Gene: HSP7Q, SSQ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 126
UniProt ID: Q05931

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006879 - intracellular iron ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

750728

GRPE
GrpE protein homolog, mitochondrial

3

6

Small-scale

0.861

High

478533

HSP77
Import motor subunit, mitochondrial

3

17

Small-scale

0.827

High

974339

ISU1
Iron sulfur cluster assembly protein 1, mitochondrial

5

6

Small-scale

0.714

High

860024

JAC1
J-type co-chaperone JAC1, mitochondrial

1

1

Small-scale

0.647

High

492454

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.575

High

494977

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.575

High

512754

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.575

High

754712

SSZ1
Ribosome-associated complex subunit SSZ1

1

14

High-throughput

0.575

High

615376

GYS1
Glycogen [starch] synthase isoform 1

1

4

High-throughput

0.536

High

663339

TF2B
Transcription initiation factor IIB

2

8

High-throughput

0.521

High

766852

ISC1
Inositol phosphosphingolipids phospholipase C

1

1

Small-scale

0.501

High

634192

SRO9
RNA-binding protein SRO9

1

13

High-throughput

0.489

High

980154

ERB1
Ribosome biogenesis protein ERB1

1

13

High-throughput

0.489

High

357375

RMAR
Small ribosomal subunit protein uS3m

1

4

High-throughput

0.479

High

558680

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

567998

MDHM
Malate dehydrogenase, mitochondrial

1

9

High-throughput

0.479

High

630831

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

13

High-throughput

0.479

High

688825

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

17

High-throughput

0.479

High

694246

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

7

High-throughput

0.479

High

699999

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

4

High-throughput

0.479

High

705661

HSP78
Heat shock protein 78, mitochondrial

1

19

High-throughput

0.479

High

767298

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

15

High-throughput

0.479

High

803418

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

15

High-throughput

0.479

High

967650

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

5

Small-scale

0.479

High

972475

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

5

Small-scale

0.479

High

982697

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

4

High-throughput

0.479

High

985290

ISU2
Iron sulfur cluster assembly protein 2, mitochondrial

1

6

High-throughput

0.479

High

368412

EF1A
Elongation factor 1-alpha

1

6

High-throughput

0.445

High

381488

GAL1
Galactokinase

1

5

High-throughput

0.445

High

404375

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

4

High-throughput

0.445

High

420168

TOP2
DNA topoisomerase 2

1

9

High-throughput

0.445

High

423484

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

3

High-throughput

0.445

High

434547

OAT
Ornithine aminotransferase

1

5

High-throughput

0.445

High

550122

CSK21
Casein kinase II subunit alpha

1

20

High-throughput

0.445

High

594366

PP11
Serine/threonine-protein phosphatase PP1-1

1

20

High-throughput

0.445

High

607341

RFA1
Replication factor A protein 1

1

7

High-throughput

0.445

High

618798

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

20

High-throughput

0.445

High

622194

MCM3
DNA replication licensing factor MCM3

1

20

High-throughput

0.445

High

635713

TAH1
TPR repeat-containing protein associated with Hsp90

1

20

High-throughput

0.445

High

686144

CHMU
Chorismate mutase

1

3

High-throughput

0.445

High

689121

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

12

High-throughput

0.445

High

696755

RTG2
Retrograde regulation protein 2

1

4

High-throughput

0.445

High

697650

FADH
S-(hydroxymethyl)glutathione dehydrogenase

1

15

High-throughput

0.445

High

703174

UFD4
Ubiquitin fusion degradation protein 4

1

17

High-throughput

0.445

High

727667

TCTP
Translationally-controlled tumor protein homolog

1

6

High-throughput

0.445

High

732596

T2EA
Transcription initiation factor IIE subunit alpha

1

2

High-throughput

0.445

High

741269

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

7

High-throughput

0.445

High

746346

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

7

High-throughput

0.445

High

753953

RPN1
26S proteasome regulatory subunit RPN1

1

11

High-throughput

0.445

High

758098

BFR1
Nuclear segregation protein BFR1

1

2

High-throughput

0.445

High

758966

SHC1
Protein SHC1

1

9

High-throughput

0.445

High

764137

RV167
Reduced viability upon starvation protein 167

1

19

High-throughput

0.445

High

764890

SNF7
Vacuolar-sorting protein SNF7

1

13

High-throughput

0.445

High

770336

RUXG
Small nuclear ribonucleoprotein G

1

9

High-throughput

0.445

High

774557

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

11

High-throughput

0.445

High

777102

SYA
Alanine--tRNA ligase, mitochondrial

1

13

High-throughput

0.445

High

810918

MTR4
ATP-dependent RNA helicase DOB1

1

20

High-throughput

0.445

High

811462

TCPQ
T-complex protein 1 subunit theta

1

10

High-throughput

0.445

High

812594

MET5
Sulfite reductase [NADPH] subunit beta

1

9

High-throughput

0.445

High

822928

VATG
V-type proton ATPase subunit G

1

6

High-throughput

0.445

High

826563

LYS4
Homoaconitase, mitochondrial

1

18

High-throughput

0.445

High

857277

ACS2
Acetyl-coenzyme A synthetase 2

1

6

High-throughput

0.445

High

858869

APC10
Anaphase-promoting complex subunit DOC1

1

3

High-throughput

0.445

High

859275

INO80
Chromatin-remodeling ATPase INO80

1

20

High-throughput

0.445

High

865813

FMP41
Uncharacterized mitochondrial hydrolase FMP41

1

2

High-throughput

0.445

High

865876

NSG2
Protein NSG2

1

4

High-throughput

0.445

High

965009

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

17

High-throughput

0.445

High

968082

PRS8
26S proteasome regulatory subunit 8 homolog

1

12

High-throughput

0.445

High

979435

ARMT1
Damage-control phosphatase YMR027W

1

2

High-throughput

0.445

High

985285

IWR1
RNA polymerase II nuclear localization protein IWR1

1

3

High-throughput

0.445

High

985286

FRDA
Frataxin homolog, mitochondrial

1

1

Small-scale

0.445

High

985287

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

18

High-throughput

0.445

High

985289

LKHA4
Leucine aminopeptidase 2

1

11

High-throughput

0.445

High

985292

RPIA
Ribose-5-phosphate isomerase

1

2

High-throughput

0.445

High

985293

RUXE
Small nuclear ribonucleoprotein E

1

3

High-throughput

0.445

High

985295

TCB1
Tricalbin-1

1

11

High-throughput

0.445

High

985294

ERP3
Protein ERP3

1

15

High-throughput

0.439

High

701585

SC61A
Protein transport protein SEC61

1

3

High-throughput

0.437

High

977671

MSS11
Transcription activator MSS11

1

0

High-throughput

0.426

High

985284

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit CNL1

1

0

High-throughput

0.426

High

404916

RL9A
Large ribosomal subunit protein uL6A

1

7

High-throughput

0.407

High

479039

RL43A
Large ribosomal subunit protein eL43A

1

2

High-throughput

0.407

High

606760

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

9

High-throughput

0.407

High

618246

AATC
Aspartate aminotransferase, cytoplasmic

1

4

High-throughput

0.407

High

630537

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.407

High

655580

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

6

High-throughput

0.407

High

655653

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

5

High-throughput

0.407

High

675437

PSB5
Proteasome subunit beta type-5

1

9

High-throughput

0.407

High

687485

EF2
Elongation factor 2

1

14

High-throughput

0.407

High

689964

ASF1
Histone chaperone ASF1

1

3

High-throughput

0.407

High

690979

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

16

High-throughput

0.407

High

693365

RPN2
26S proteasome regulatory subunit RPN2

1

11

High-throughput

0.407

High

693884

SRP40
Suppressor protein SRP40

1

5

High-throughput

0.407

High

693939

MED18
Mediator of RNA polymerase II transcription subunit 18

1

5

High-throughput

0.407

High

701346

SPT4
Transcription elongation factor SPT4

1

2

High-throughput

0.407

High

731932

ELF1
Transcription elongation factor 1

1

2

High-throughput

0.407

High

733196

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

3

High-throughput

0.407

High

744698

TAF5
Transcription initiation factor TFIID subunit 5

1

14

High-throughput

0.407

High

750151

IF5
Eukaryotic translation initiation factor 5

1

5

High-throughput

0.407

High

755755

ORC6
Origin recognition complex subunit 6

1

4

High-throughput

0.407

High

765986

DPO5
rDNA transcriptional regulator POL5

1

4

High-throughput

0.407

High

772886

RIC1
Guanine nucleotide exchange factor subunit RIC1

1

3

High-throughput

0.407

High

777324

SA185
SIT4-associating protein SAP185

1

10

High-throughput

0.407

High

797278

IES1
Ino eighty subunit 1

1

2

High-throughput

0.407

High

812125

MOG1
Nuclear import protein MOG1

1

4

High-throughput

0.407

High

812219

EAF6
Chromatin modification-related protein EAF6

1

2

High-throughput

0.407

High

812625

HIR3
Histone transcription regulator 3

1

2

High-throughput

0.407

High

837467

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

7

High-throughput

0.407

High

842081

SPT20
Transcription factor SPT20

1

4

High-throughput

0.407

High

858798

MNT2
Alpha-1,3-mannosyltransferase MNT2

1

10

High-throughput

0.407

High

860739

UTP22
U3 small nucleolar RNA-associated protein 22

1

2

High-throughput

0.407

High

860787

DRN1
CWF19-like protein DRN1

1

2

High-throughput

0.407

High

860808

RRP46
Exosome complex component RRP46

1

9

High-throughput

0.407

High

863640

COPA
Coatomer subunit alpha

1

17

High-throughput

0.407

High

866011

EAF7
Chromatin modification-related protein EAF7

1

5

High-throughput

0.407

High

902068

H3
Histone H3

1

14

High-throughput

0.407

High

979447

PUF6
Pumilio homology domain family member 6

1

14

High-throughput

0.407

High

984163

RT103
Regulator of Ty1 transposition protein 103

1

5

High-throughput

0.407

High

984307

RRP45
Exosome complex component RRP45

1

11

High-throughput

0.407

High

985283

YL455
PWWP domain-containing protein YLR455W

1

2

High-throughput

0.407

High

985288

THP1
Nuclear mRNA export protein THP1

1

5

High-throughput

0.407

High

985291

MAK21
Ribosome biogenesis protein MAK21

1

8

High-throughput

0.407

High

985296

EFG1P
rRNA-processing protein EFG1

1

3

High-throughput

0.407

High

985297

ATG40
Autophagy-related protein 40

1

2

High-throughput

0.407

High

549496

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.307

High

702720

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024