Protein: DFM1
DER1-like family member protein 1

Gene: DFM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q12743

Gene Ontology (top 5):
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 - endoplasmic reticulum
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0036503 - ERAD pathway
GO:0044877 - protein-containing complex binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636790

CDC48
Cell division control protein 48

6

7

Small-scale

0.726

High

1015737

DFM1
DER1-like family member protein 1

1

14

Small-scale

0.665

High

748979

UBX7
UBX domain-containing protein 7

2

9

Small-scale

0.625

High

977380

USA1
U1 SNP1-associating protein 1

2

1

Small-scale

0.625

High

748216

DER1
Degradation in the endoplasmic reticulum protein 1

1

1

Small-scale

0.618

High

984793

HRD3
ERAD-associated E3 ubiquitin-protein ligase component HRD3

2

3

Small-scale

0.611

High

993387

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

2

8

Small-scale

0.611

High

979140

UBX2
UBX domain-containing protein 2

2

1

Small-scale

0.601

High

520371

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

2

0

Small-scale

0.559

High

707257

NPL4
Nuclear protein localization protein 4

1

2

Small-scale

0.536

High

1015738

OS9
Protein OS-9 homolog

1

1

Small-scale

0.536

High

858719

UFD1
Ubiquitin fusion degradation protein 1

1

1

Small-scale

0.515

High

710588

UBX1
UBX domain-containing protein 1

1

0

Small-scale

0.513

High

964752

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.501

High

976099

PEX29
Peroxisomal membrane protein PEX29

1

0

High-throughput

0.486

High

753994

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

771599

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

Small-scale

0.479

High

1015739

ENV10
SRP-independent targeting protein 2

1

2

High-throughput

0.479

High

679947

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

Small-scale

0.458

High

747499

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

560838

BIP
Endoplasmic reticulum chaperone BiP

1

1

Small-scale

0.445

High

407418

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

522432

STE6
Alpha-factor-transporting ATPase

1

2

Small-scale

0.437

High

586223

PMA2
Plasma membrane ATPase 2

1

4

High-throughput

0.437

High

663775

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

704094

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

2

Small-scale

0.437

High

711135

YKK0
Probable intramembrane protease YKL100C

1

2

Small-scale

0.437

High

765779

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

2

High-throughput

0.437

High

743752

HMT1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.417

High

450252

HSP73
Heat shock protein SSA3

1

5

High-throughput

0.407

High

492962

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.407

High

495406

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.407

High

513347

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

695893

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.407

High

766295

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

762840

UIP3
ULP1-interacting protein 3

1

0

High-throughput

0.265

Low

811268

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.265

Low

693768

IME2
Meiosis induction protein kinase IME2/SME1

1

0

High-throughput

0.261

Low

357395

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

426225

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

482532

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

694324

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

752343

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

797666

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

826228

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.249

Low

966055

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024