HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 165
+	Hs
		923633 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		673675 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		PPIF_HUMAN (3-164): 6.26e-92: 267: 76.54
+	Hs
		892306 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		923641 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		893876 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		900356 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00
+	Hs
		901053 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		PPIE_HUMAN (2-163): 2.08e-88: 262: 67.28
+	Hs
		436246 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00