Protein: KEX1
Pheromone-processing carboxypeptidase KEX1 (EC 3.4.16.6) (Carboxypeptidase D) (Killer expression defective protein 1)

Gene: KEX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P09620

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0004185 - serine-type carboxypeptidase activity
GO:0005802 - trans-Golgi network
GO:0006508 - proteolysis
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

452502

KEX1
Pheromone-processing carboxypeptidase KEX1

1

2

High-throughput

0.698

High

452508

KEX2
Kexin

2

1

High-throughput

0.614

High

452524

ATC5
Phospholipid-transporting ATPase DNF1

2

2

High-throughput

0.614

High

452543

ATC3
Phospholipid-transporting ATPase DRS2

2

2

High-throughput

0.614

High

452546

SHO1
High osmolarity signaling protein SHO1

2

0

High-throughput

0.587

High

452545

FLC2
Flavin carrier protein 2

2

1

High-throughput

0.559

High

452510

HNM1
Choline transport protein

1

1

High-throughput

0.541

High

452512

HXT2
High-affinity glucose transporter HXT2

1

2

High-throughput

0.541

High

452519

ITR1
Myo-inositol transporter 1

1

2

High-throughput

0.541

High

452556

MUP1
High-affinity methionine permease

1

1

High-throughput

0.541

High

452579

FLC1
Flavin carrier protein 1

1

1

High-throughput

0.541

High

452583

RBD2
Rhomboid-type serine protease 2

1

2

High-throughput

0.541

High

452505

SEC7
Protein transport protein SEC7

1

0

High-throughput

0.518

High

452515

CDC50
Phospholipid-transporting ATPase accessory subunit CDC50

1

0

High-throughput

0.518

High

452520

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

0

High-throughput

0.518

High

452532

GEF1
Anion/proton exchange transporter GEF1

1

0

High-throughput

0.518

High

452542

VATF
V-type proton ATPase subunit F

1

0

High-throughput

0.518

High

452567

DOP1
Protein dopey

1

0

High-throughput

0.518

High

452572

DPP1
Diacylglycerol pyrophosphate phosphatase 1

1

0

High-throughput

0.518

High

452573

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.518

High

452574

OPY2
Protein OPY2

1

0

High-throughput

0.518

High

452577

BSC6
Bypass of stop codon protein 6

1

0

High-throughput

0.518

High

452581

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.518

High

452507

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.504

High

452506

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.494

High

452521

HXT1
Low-affinity glucose transporter HXT1

1

2

High-throughput

0.494

High

452535

FTH1
Iron transporter FTH1

1

1

High-throughput

0.494

High

452547

FTR1
Plasma membrane iron permease

1

1

High-throughput

0.494

High

452552

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.494

High

452565

YMD8
Putative nucleotide-sugar transporter YMD8

1

1

High-throughput

0.494

High

452514

BPH1
Beige protein homolog 1

1

1

High-throughput

0.479

High

452526

PTM1
Membrane protein PTM1

1

1

High-throughput

0.479

High

452537

YHB7
Uncharacterized membrane protein YHL071W

1

1

High-throughput

0.479

High

452557

AIM14
Probable metalloreductase AIM14

1

1

High-throughput

0.479

High

452562

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

2

High-throughput

0.479

High

452585

ATC4
Phospholipid-transporting ATPase DNF2

1

2

High-throughput

0.479

High

452523

GDA1
Guanosine-diphosphatase

1

0

High-throughput

0.458

High

452528

NIP80
Protein NIP100

1

1

High-throughput

0.439

High

452564

ANY1
Scramblase ANY1

1

0

High-throughput

0.438

High

452516

PEX3
Peroxisomal biogenesis factor 3

1

2

High-throughput

0.437

High

452517

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

452559

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.437

High

452570

TMN2
Transmembrane 9 superfamily member 2

1

1

High-throughput

0.437

High

452525

TMN1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.417

High

452504

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.407

High

452509

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

452548

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.407

High

452518

CHS3
Chitin synthase 3

3

0

High-throughput

0.343

High

452530

AUR1
Inositol phosphorylceramide synthase catalytic subunit AUR1

2

0

High-throughput

0.320

High

452531

TVP38
Golgi apparatus membrane protein TVP38

2

0

High-throughput

0.320

High

452540

AKR1
Palmitoyltransferase AKR1

2

0

High-throughput

0.320

High

452549

PEP8
Carboxypeptidase Y-deficient protein 8

2

0

High-throughput

0.319

High

452529

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

2

0

High-throughput

0.305

High

440839

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

2

0

High-throughput

0.298

High

452536

FKS1
1,3-beta-glucan synthase component FKS1

2

0

High-throughput

0.298

High

452522

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.282

High

452527

DUR3
Urea active transporter

1

0

High-throughput

0.282

High

452534

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.282

High

452538

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.282

High

452539

VPS45
Vacuolar protein sorting-associated protein 45

1

0

High-throughput

0.282

High

452554

COPD
Coatomer subunit delta

1

0

High-throughput

0.282

High

452560

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.282

High

452566

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.282

High

452569

PLM2
Protein PLM2

1

0

High-throughput

0.282

High

452578

SNX3
Sorting nexin-3

1

0

High-throughput

0.282

High

452580

PIN2
[PSI+] induction protein 2

1

0

High-throughput

0.282

High

452513

PUF4
Pumilio homology domain family member 4

1

0

High-throughput

0.269

Low

452575

PBP4
Protein PBP4

1

0

High-throughput

0.269

Low

452584

ISA2
Iron-sulfur assembly protein 2

1

0

High-throughput

0.269

Low

452533

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.249

Low

452541

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

High-throughput

0.249

Low

452544

PHO90
Low-affinity phosphate transporter PHO90

1

0

High-throughput

0.249

Low

452555

GNP1
High-affinity glutamine permease

1

0

High-throughput

0.249

Low

452558

VOA1
V0 assembly protein 1

1

0

High-throughput

0.249

Low

452563

YM8V
Uncharacterized protein YMR295C

1

0

High-throughput

0.249

Low

452568

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

452571

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.249

Low

452576

AIM6
Altered inheritance of mitochondria protein 6

1

0

High-throughput

0.249

Low

452582

MRH1
Protein MRH1

1

0

High-throughput

0.249

Low

452511

EPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.238

Low

452551

COPB
Coatomer subunit beta

1

0

High-throughput

0.238

Low

452561

PDR12
ATP-dependent permease PDR12

1

0

High-throughput

0.238

Low

367635

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

452503

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low

452550

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

452553

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024