Protein: ACT2
Actin-42A (EC 3.6.4.-)

Gene: ACT2, Act42A
Organism: Drosophila melanogaster
Interactions: 58
UniProt ID: P02572

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0015629 - actin cytoskeleton
GO:0016787 - hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387000

Q9VPX6
Adenylyl cyclase-associated protein

4

20

Small-scale

0.878

High

386972

BRM
ATP-dependent helicase brm

4

17

Small-scale

0.878

High

386963

ACT4
Actin, larval muscle

3

18

Small-scale

0.840

High

386976

ACT6
Actin, indirect flight muscle

3

19

High-throughput

0.839

High

386962

ACT2
Actin-42A

2

18

High-throughput

0.767

High

386967

ACT5
Actin-87E

2

18

High-throughput

0.767

High

386974

ACT3
Actin-57B

2

18

High-throughput

0.767

High

122285

M9PI41
non-specific serine/threonine protein kinase

1

7

Small-scale

0.618

High

386970

SPTCA
Spectrin alpha chain

1

20

Small-scale

0.618

High

387002

Q9VR61
non-specific serine/threonine protein kinase

1

11

High-throughput

0.618

High

386985

Q8SY43
LD24110p

1

13

High-throughput

0.590

High

387001

Q9VPX7
Capulet, isoform A

1

20

High-throughput

0.590

High

386997

GRCR1
Glutaredoxin domain-containing cysteine-rich protein CG31559

2

6

High-throughput

0.542

High

387013

Q9W4A9
Rho GTPase activating protein at 5A, isoform A

1

17

High-throughput

0.514

High

386964

AST5
Achaete-scute complex protein T5

1

4

Small-scale

0.504

High

386965

AST4
Achaete-scute complex protein T4

1

5

Small-scale

0.504

High

386994

Q9VF03
Brahma associated protein 155 kDa

1

9

Small-scale

0.501

High

386966

OTU
Deubiquitinase otu

1

5

Small-scale

0.479

High

386968

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

4

High-throughput

0.479

High

386971

OSKA
Maternal effect protein oskar

1

4

Small-scale

0.479

High

386986

Q8T0T2
GH09296p

1

5

Small-scale

0.479

High

386991

ANLN
Anillin

1

10

Small-scale

0.479

High

386979

Q5U0Y0
Paired amphipathic helix protein Sin3a

1

4

High-throughput

0.464

High

387004

Q9VVQ1
Allatostatin C receptor 1

1

6

High-throughput

0.464

High

386978

STX1A
Syntaxin-1A

1

1

High-throughput

0.457

High

386973

RAC1
Ras-related protein Rac1

1

7

High-throughput

0.445

High

386977

PCL
Polycomb protein Pcl

1

15

High-throughput

0.445

High

386982

Q7JZT9
allantoinase

1

4

High-throughput

0.445

High

386983

Q7K490
SD03973p

1

8

High-throughput

0.445

High

386988

DNAT
Arylalkylamine N-acetyltransferase 1

1

1

High-throughput

0.445

High

386989

Q9I7L1
Arrestin C-terminal-like domain-containing protein

1

13

High-throughput

0.445

High

386996

Q9VKQ5
GEO07393p1

1

2

High-throughput

0.445

High

119552

M9PAY7
Pi3K21B, isoform C

1

16

High-throughput

0.437

High

386969

DA
Protein daughterless

1

1

Small-scale

0.437

High

386984

LASP1
LIM and SH3 domain protein Lasp

1

20

Small-scale

0.437

High

386993

Q9VEV3
Tetratricopeptide repeat protein 1

1

12

High-throughput

0.437

High

387006

PGPLE
Peptidoglycan-recognition protein LE

1

5

High-throughput

0.437

High

387009

Q9VYT3
FI23714p1

1

1

Small-scale

0.437

High

386990

PITC1
Cytoplasmic phosphatidylinositol transfer protein 1

1

0

High-throughput

0.426

High

386995

Q9VFX0
Aminopeptidase

1

0

High-throughput

0.426

High

387007

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.426

High

386975

HEM
Membrane-associated protein Hem

1

5

Small-scale

0.417

High

386981

Q6NR18
phospholipase D

1

2

High-throughput

0.417

High

386992

Q9VC48
Methionine aminopeptidase

1

3

High-throughput

0.417

High

92080

D1Z394
Entomoglyceroporin 4, isoform E

1

1

High-throughput

0.407

High

386987

Q8T3J1
SD02419p

1

1

High-throughput

0.407

High

387008

Q9VXV4
RH04535p

1

1

High-throughput

0.407

High

387010

Q9VZS1
protein-serine/threonine phosphatase

1

2

High-throughput

0.407

High

387012

Q9W478
RE43153p

1

1

High-throughput

0.407

High

387014

Q9W4L9
IP04124p

1

1

High-throughput

0.407

High

197986

AMYR
Alpha-amylase-related protein

1

0

High-throughput

0.232

Low

386980

Q6IHN1
GEO11035p1

1

0

High-throughput

0.232

Low

386998

Q9VP89
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

386999

Q9VPA4
MIP08452p

1

0

High-throughput

0.232

Low

387003

Q9VTV9
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.232

Low

387005

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3 homolog

1

0

High-throughput

0.232

Low

387011

Q9W1H6
GH04238p

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025