Protein: MED19
Mediator of RNA polymerase II transcription subunit 19 (Hypoxic gene repressor protein 3) (Mediator complex subunit 19) (Negative regulator of URS2 protein 3) (SNF1 suppressor protein 7)

Gene: MED19, ROX3
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P25046

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001113 - transcription open complex formation at RNA polymerase II promoter
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626029

MED6
Mediator of RNA polymerase II transcription subunit 6

6

0

Small-scale

0.887

High

626044

MED7
Mediator of RNA polymerase II transcription subunit 7

6

0

Small-scale

0.881

High

581336

MED14
Mediator of RNA polymerase II transcription subunit 14

5

0

Small-scale

0.861

High

626043

MED10
Mediator of RNA polymerase II transcription subunit 10

4

0

High-throughput

0.836

High

626017

MED18
Mediator of RNA polymerase II transcription subunit 18

8

0

Small-scale

0.714

High

626015

MED17
Mediator of RNA polymerase II transcription subunit 17

8

0

Small-scale

0.712

High

586262

MED15
Mediator of RNA polymerase II transcription subunit 15

6

0

Small-scale

0.695

High

626019

MED9
Mediator of RNA polymerase II transcription subunit 9

6

0

Small-scale

0.694

High

626026

MED8
Mediator of RNA polymerase II transcription subunit 8

6

0

Small-scale

0.691

High

626036

MED3
Mediator of RNA polymerase II transcription subunit 3

6

0

Small-scale

0.689

High

626039

MED21
Mediator of RNA polymerase II transcription subunit 21

5

0

Small-scale

0.679

High

626048

MED4
Mediator of RNA polymerase II transcription subunit 4

5

0

Small-scale

0.679

High

626011

SRB8
Mediator of RNA polymerase II transcription subunit 12

4

0

Small-scale

0.654

High

626014

MED16
Mediator of RNA polymerase II transcription subunit 16

4

0

High-throughput

0.654

High

626047

MED1
Mediator of RNA polymerase II transcription subunit 1

4

0

High-throughput

0.654

High

626040

MED5
Mediator of RNA polymerase II transcription subunit 5

4

0

Small-scale

0.649

High

587819

AP1
AP-1-like transcription factor YAP1

3

0

Small-scale

0.616

High

626016

MED22
Mediator of RNA polymerase II transcription subunit 22

3

0

Small-scale

0.616

High

626021

MED20
Mediator of RNA polymerase II transcription subunit 20

3

0

High-throughput

0.616

High

626031

SSN2
Mediator of RNA polymerase II transcription subunit 13

3

0

High-throughput

0.616

High

626033

SSN3
Meiotic mRNA stability protein kinase SSN3

3

0

High-throughput

0.616

High

626049

MED11
Mediator of RNA polymerase II transcription subunit 11

3

0

High-throughput

0.616

High

626027

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

High-throughput

0.576

High

626045

MED2
Mediator of RNA polymerase II transcription subunit 2

2

0

High-throughput

0.576

High

626034

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

589539

SFL1
Flocculation suppression protein

1

0

Small-scale

0.493

High

626030

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

626032

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

626037

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.493

High

626046

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

381593

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

High-throughput

0.486

High

626024

MYO3
Myosin-3

1

1

High-throughput

0.464

High

626042

MYO5
Myosin-5

1

1

High-throughput

0.464

High

626022

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.458

High

626023

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

626038

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.458

High

510351

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

626025

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

375288

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.426

High

498802

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

626012

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.407

High

626013

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.407

High

626018

RM06
Large ribosomal subunit protein uL6m

2

0

High-throughput

0.307

High

367765

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

405134

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.232

Low

405954

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.232

Low

534889

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.232

Low

535185

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.232

Low

555831

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

626020

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

626028

RL14B
Large ribosomal subunit protein eL14B

1

0

High-throughput

0.232

Low

626035

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.232

Low

626041

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024