Protein: TNNC2
Troponin C, skeletal muscle

Gene: TNNC2
Organism: Homo sapiens
Interactions: 81
UniProt ID: P02585

Gene Ontology (top 5):
GO:0003009 - skeletal muscle contraction
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005861 - troponin complex
GO:0006937 - regulation of muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387095

TNNI3
Troponin I, cardiac muscle

2

8

High-throughput

0.817

High

290283

KS6A4
Ribosomal protein S6 kinase alpha-4

2

8

High-throughput

0.776

High

387099

CALL3
Calmodulin-like protein 3

1

6

High-throughput

0.691

High

387104

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

12

High-throughput

0.691

High

387106

ACTA
Actin, aortic smooth muscle

1

3

High-throughput

0.691

High

387112

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

1

7

High-throughput

0.691

High

387113

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

7

High-throughput

0.691

High

387157

NOSIP
Nitric oxide synthase-interacting protein

3

0

High-throughput

0.638

High

387118

DCAF6
DDB1- and CUL4-associated factor 6

3

0

High-throughput

0.622

High

387139

AURKB
Aurora kinase B

1

9

High-throughput

0.618

High

387111

KCAB2
Voltage-gated potassium channel subunit beta-2

2

2

High-throughput

0.612

High

387102

ITPI2
Protein ITPRID2

2

2

High-throughput

0.601

High

387103

PML
Protein PML

2

7

High-throughput

0.601

High

387119

Q6FGX2
Troponin I, cardiac muscle

1

8

High-throughput

0.594

High

387125

TBCD1
TBC1 domain family member 1

3

8

High-throughput

0.591

High

387109

CLM6
CMRF35-like molecule 6

1

0

High-throughput

0.578

High

181599

CETN3
Centrin-3

1

17

High-throughput

0.575

High

387115

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

4

High-throughput

0.575

High

387156

MYO6
Unconventional myosin-VI

1

16

High-throughput

0.575

High

387159

MYO5A
Unconventional myosin-Va

1

16

High-throughput

0.575

High

330553

KI20A
Kinesin-like protein KIF20A

2

9

High-throughput

0.558

High

387134

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

0

High-throughput

0.551

High

387130

MA7D3
MAP7 domain-containing protein 3

2

9

High-throughput

0.549

High

387092

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

5

High-throughput

0.536

High

387114

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.536

High

387123

MCAF1
Activating transcription factor 7-interacting protein 1

1

7

High-throughput

0.536

High

387124

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.536

High

387093

PGAM2
Phosphoglycerate mutase 2

1

1

High-throughput

0.515

High

287642

KS6A5
Ribosomal protein S6 kinase alpha-5

1

10

High-throughput

0.514

High

318233

MYO1D
Unconventional myosin-Id

1

20

High-throughput

0.514

High

387120

IQCE
IQ domain-containing protein E

1

4

High-throughput

0.514

High

387155

MYO5B
Unconventional myosin-Vb

1

13

High-throughput

0.514

High

261686

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.513

High

284525

ECI2
Enoyl-CoA delta isomerase 2

1

0

High-throughput

0.513

High

387098

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.513

High

387105

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.513

High

387108

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.513

High

387141

SPS2
Selenide, water dikinase 2

1

0

High-throughput

0.513

High

387153

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.513

High

387154

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.513

High

387151

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.493

High

387100

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

2

High-throughput

0.489

High

387133

TM131
Transmembrane protein 131

1

1

High-throughput

0.489

High

387135

MAML1
Mastermind-like protein 1

1

1

High-throughput

0.489

High

387140

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

7

High-throughput

0.489

High

387143

HIRP3
HIRA-interacting protein 3

1

1

High-throughput

0.489

High

387145

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

3

High-throughput

0.489

High

387146

CLSPN
Claspin

1

2

High-throughput

0.489

High

387096

SL9A1
Sodium/hydrogen exchanger 1

1

0

High-throughput

0.481

High

387107

KIF23
Kinesin-like protein KIF23

1

7

High-throughput

0.479

High

387116

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

387147

ANLN
Anillin

1

1

High-throughput

0.479

High

387149

RNF12
E3 ubiquitin-protein ligase RLIM

1

3

High-throughput

0.479

High

51023

PKHG3
Pleckstrin homology domain-containing family G member 3

1

2

High-throughput

0.445

High

336311

SVIL
Supervillin

1

1

High-throughput

0.445

High

387101

TMOD1
Tropomodulin-1

1

1

High-throughput

0.445

High

387127

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.426

High

387160

PXMP4
Peroxisomal membrane protein 4

1

0

High-throughput

0.426

High

387121

DUX4C
Double homeobox protein 4C

1

2

High-throughput

0.417

High

296183

SCO1
Protein SCO1 homolog, mitochondrial

1

2

High-throughput

0.407

High

387094

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

1

High-throughput

0.407

High

387097

HEMH
Ferrochelatase, mitochondrial

1

4

High-throughput

0.407

High

387110

NEXN
Nexilin

1

1

High-throughput

0.407

High

387150

TMOD3
Tropomodulin-3

1

1

High-throughput

0.407

High

155387

DHSD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

1

0

High-throughput

0.279

Low

387091

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.279

Low

387117

ZNF74
Zinc finger protein 74

1

0

High-throughput

0.279

Low

387122

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

0

High-throughput

0.279

Low

387126

TSN33
Tetraspanin-33

1

0

High-throughput

0.279

Low

387128

PRR15
Proline-rich protein 15

1

0

High-throughput

0.279

Low

387131

DTD1
D-aminoacyl-tRNA deacylase 1

1

0

High-throughput

0.279

Low

387132

CG033
Uncharacterized protein C7orf33

1

0

High-throughput

0.279

Low

387137

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

0

High-throughput

0.279

Low

387142

CNPD1
Protein CNPPD1

1

0

High-throughput

0.279

Low

387144

RSH6A
Radial spoke head protein 6 homolog A

1

0

High-throughput

0.279

Low

387148

CT141
Uncharacterized protein C20orf141

1

0

High-throughput

0.279

Low

387158

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.279

Low

387138

TM186
Transmembrane protein 186

1

0

High-throughput

0.269

Low

387129

NNRD
ATP-dependent

1

0

High-throughput

0.232

Low

387136

COR2A
Coronin-2A

1

0

High-throughput

0.232

Low

387152

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025