Protein: HIS4
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16) (5-proFAR isomerase) (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase)

Gene: HIS4, HIS6
Organism: Saccharomyces cerevisiae S288C
Interactions: 12
UniProt ID: P40545

Gene Ontology (top 5):
GO:0000105 - L-histidine biosynthetic process
GO:0003949 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438715

SC160
Protein SCP160

1

0

High-throughput

0.493

High

826188

YL179
Uncharacterized protein YLR179C

1

0

High-throughput

0.493

High

509591

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

602504

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

792087

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

826186

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

545172

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

818963

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

826185

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.438

High

392859

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

524196

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

826187

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025