Protein: COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.15.45) (2-methoxy-6-polyprenolphenol 4-hydroxylase) (EC 1.14.15.46) (Ubiquinone C4-deaminase) (EC 3.5.-.-)

Gene: COQ6
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P53318

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006744 - ubiquinone biosynthetic process
GO:0008681 - 2-octaprenyl-6-methoxyphenol hydroxylase activity
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919606

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

4

1

Small-scale

0.686

High

878363

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

2

3

Small-scale

0.584

High

626833

HSP60
Heat shock protein 60, mitochondrial

2

2

Small-scale

0.571

High

835599

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

2

0

Small-scale

0.559

High

453713

PYR1
Multifunctional protein URA2

2

0

Small-scale

0.547

High

150075

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

1

1

Small-scale

0.479

High

694479

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

3

Small-scale

0.479

High

697334

COQ8
Atypical kinase COQ8, mitochondrial

1

2

Small-scale

0.479

High

919604

YHM2
Citrate/oxoglutarate carrier protein

1

1

Small-scale

0.479

High

919607

MMT2
Mitochondrial metal transporter 2

1

1

Small-scale

0.479

High

510687

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

752557

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

815188

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

816087

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

Small-scale

0.458

High

881400

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

527284

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

592399

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

671674

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

739897

RPD3
Histone deacetylase RPD3

1

0

High-throughput

0.269

Low

919605

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.269

Low

416902

CDC25
Cell division control protein 25

1

0

High-throughput

0.261

Low

707756

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

754441

NPL4
Nuclear protein localization protein 4

1

0

Small-scale

0.249

Low

826187

HIS4
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase

1

0

Small-scale

0.249

Low

917530

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.249

Low

919602

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.249

Low

919603

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

919608

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

919609

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

444581

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.232

Low

545717

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025