Protein: SPEE
Spermidine synthase SPE3 (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase)

Gene: SPEE, SPE3
Organism: Saccharomyces cerevisiae S288C
Interactions: 26
UniProt ID: Q12074

Gene Ontology (top 5):
GO:0004766 - spermidine synthase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008295 - spermidine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084236

SPSY
Spermine synthase SPE4

5

10

High-throughput

0.921

High

850245

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

1026854

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.536

High

448240

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

795588

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

1038274

YP068
Uncharacterized protein YPL068C

1

1

High-throughput

0.479

High

671225

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

708477

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

802439

RS20
Small ribosomal subunit protein uS10

1

0

Small-scale

0.458

High

806830

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

815271

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

918713

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

923150

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.458

High

1030604

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.458

High

1044827

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1084232

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

1084234

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

592564

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

820069

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

394996

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

1061659

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.269

Low

795262

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

1065528

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

1084213

UPPS
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.249

Low

1084233

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

1084235

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025