Protein: RSMB
Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB)

Gene: RSMB, SMB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 127
UniProt ID: P40018

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

766915

SMD3
Small nuclear ribonucleoprotein Sm D3

8

15

Small-scale

0.964

High

766943

SMD1
Small nuclear ribonucleoprotein Sm D1

7

4

Small-scale

0.960

High

766971

RU2A
U2 small nuclear ribonucleoprotein A'

6

4

Small-scale

0.940

High

704673

PRP8
Pre-mRNA-splicing factor 8

5

2

High-throughput

0.922

High

766969

LUC7
Protein LUC7

5

1

High-throughput

0.919

High

766941

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

5

9

Small-scale

0.915

High

766911

RUXG
Small nuclear ribonucleoprotein G

5

13

High-throughput

0.912

High

766936

RUXF
Small nuclear ribonucleoprotein F

5

5

High-throughput

0.912

High

766937

LSM3
U6 snRNA-associated Sm-like protein LSm3

5

19

Small-scale

0.908

High

766909

LSM4
U6 snRNA-associated Sm-like protein LSm4

4

6

Small-scale

0.894

High

731728

SN114
Pre-mRNA-splicing factor SNU114

4

3

High-throughput

0.892

High

766960

SMD2
Small nuclear ribonucleoprotein Sm D2

4

4

High-throughput

0.892

High

586492

PRP9
Pre-mRNA-splicing factor PRP9

4

2

High-throughput

0.886

High

766917

LSM8
U6 snRNA-associated Sm-like protein LSm8

4

14

High-throughput

0.881

High

766957

RU1C
U1 small nuclear ribonucleoprotein C

5

0

High-throughput

0.875

High

746294

LSM2
U6 snRNA-associated Sm-like protein LSm2

3

15

High-throughput

0.847

High

766947

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

2

High-throughput

0.847

High

766977

RUXE
Small nuclear ribonucleoprotein E

3

2

High-throughput

0.839

High

697213

BRR2
Pre-mRNA-splicing helicase BRR2

8

11

Small-scale

0.745

High

766944

CUS1
Cold sensitive U2 snRNA suppressor 1

6

2

High-throughput

0.730

High

766939

NAM8
Protein NAM8

5

3

High-throughput

0.712

High

766967

PRP11
Pre-mRNA-splicing factor PRP11

5

2

High-throughput

0.712

High

766950

CEF1
Pre-mRNA-splicing factor CEF1

5

2

Small-scale

0.709

High

696639

RU1A
U1 small nuclear ribonucleoprotein A

6

0

Small-scale

0.702

High

766972

CWC2
Pre-mRNA-splicing factor CWC2

4

6

High-throughput

0.694

High

586408

PRP6
Pre-mRNA-splicing factor 6

4

9

High-throughput

0.691

High

589078

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

4

6

High-throughput

0.691

High

703220

PRP40
Pre-mRNA-processing protein PRP40

4

5

High-throughput

0.691

High

766920

PRP31
Pre-mRNA-processing factor 31

4

2

High-throughput

0.691

High

692401

PRP21
Pre-mRNA-splicing factor PRP21

4

2

High-throughput

0.686

High

710177

NCBP1
Nuclear cap-binding protein complex subunit 1

4

1

High-throughput

0.686

High

763232

PRP39
Pre-mRNA-processing factor 39

4

12

High-throughput

0.686

High

766921

SF3B1
U2 snRNP component HSH155

4

3

High-throughput

0.686

High

766956

RSE1
Pre-mRNA-splicing factor RSE1

4

3

High-throughput

0.686

High

766970

NCBP2
Nuclear cap-binding protein subunit 2

4

4

High-throughput

0.686

High

766976

CLF1
Pre-mRNA-splicing factor CLF1

4

12

Small-scale

0.686

High

766982

HSH49
Protein HSH49

4

4

High-throughput

0.686

High

747708

SP381
Pre-mRNA-splicing factor SPP381

5

0

High-throughput

0.684

High

692302

PRP19
Pre-mRNA-processing factor 19

4

5

Small-scale

0.683

High

766980

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

2

Small-scale

0.683

High

766954

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

5

0

High-throughput

0.682

High

766925

SNU71
U1 small nuclear ribonucleoprotein component SNU71

5

0

Small-scale

0.678

High

766958

SN309
Pre-mRNA-splicing factor SNT309

4

0

High-throughput

0.664

High

376799

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

3

3

Small-scale

0.656

High

766913

MSL1
U2 small nuclear ribonucleoprotein B''

3

9

High-throughput

0.656

High

766953

PRP42
U1 small nuclear ribonucleoprotein component PRP42

3

14

High-throughput

0.656

High

766955

SYF1
Pre-mRNA-splicing factor SYF1

3

12

High-throughput

0.656

High

766965

DIB1
Spliceosomal protein DIB1

3

2

High-throughput

0.656

High

766979

PRP46
Pre-mRNA-splicing factor PRP46

3

4

High-throughput

0.656

High

766924

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

6

High-throughput

0.650

High

766962

SP382
Pre-mRNA-splicing factor SPP382

3

0

High-throughput

0.638

High

766978

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

3

0

High-throughput

0.628

High

766910

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

2

High-throughput

0.618

High

766934

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

13

High-throughput

0.618

High

766961

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

5

High-throughput

0.618

High

766948

CWC21
Pre-mRNA-splicing factor CWC21

3

0

Small-scale

0.613

High

688719

AAR2
A1 cistron-splicing factor AAR2

2

2

High-throughput

0.611

High

766973

TGS1
Trimethylguanosine synthase

2

2

Small-scale

0.595

High

766981

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.586

High

766922

CWC23
Pre-mRNA-splicing factor CWC23

2

0

High-throughput

0.585

High

598626

ISY1
Pre-mRNA-splicing factor ISY1

2

2

High-throughput

0.584

High

655711

PRP45
Pre-mRNA-processing protein 45

2

1

High-throughput

0.584

High

746855

SLT11
Pre-mRNA-splicing factor SLT11

2

1

High-throughput

0.584

High

766914

PRP17
Pre-mRNA-processing factor 17

2

6

High-throughput

0.584

High

766966

RDS3
Pre-mRNA-splicing factor RDS3

2

1

High-throughput

0.571

High

657735

YJU2
Splicing factor YJU2

2

0

High-throughput

0.559

High

733066

NTR2
Pre-mRNA-splicing factor NTR2

2

0

High-throughput

0.559

High

766927

SYF2
Pre-mRNA-splicing factor SYF2

2

0

High-throughput

0.559

High

766929

CWC22
Pre-mRNA-splicing factor CWC22

2

0

High-throughput

0.559

High

766940

PRP38
Pre-mRNA-splicing factor 38

2

0

High-throughput

0.559

High

766952

CWC15
Pre-mRNA-splicing factor CWC15

2

0

High-throughput

0.559

High

691377

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

3

High-throughput

0.537

High

742820

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.536

High

764954

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.536

High

424871

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

745383

SEA4
SEH-associated protein 4

1

0

High-throughput

0.513

High

766918

CSN12
Cop9 signalosome complex subunit 12

1

0

High-throughput

0.513

High

766963

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

622315

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

7

Small-scale

0.501

High

766935

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.493

High

766923

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.489

High

693655

SIP1
SNF1 protein kinase subunit beta-1

1

0

High-throughput

0.486

High

766931

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.486

High

766933

SWT21
Protein SWT21

1

0

High-throughput

0.486

High

415983

DED1
ATP-dependent RNA helicase DED1

1

3

High-throughput

0.479

High

558075

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.479

High

566178

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

589430

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

7

High-throughput

0.479

High

598576

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

5

High-throughput

0.479

High

629375

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.479

High

638765

SPB4
ATP-dependent rRNA helicase SPB4

1

4

High-throughput

0.479

High

692006

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

694057

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

7

High-throughput

0.479

High

704891

LHP1
La protein homolog

1

3

High-throughput

0.479

High

755818

LSM12
Protein LSM12

1

2

High-throughput

0.479

High

756233

LIN1
Protein LIN1

1

3

High-throughput

0.479

High

766310

SNU13
13 kDa ribonucleoprotein-associated protein

1

3

High-throughput

0.479

High

766930

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.479

High

766942

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.479

High

766945

CWC27
Peptidyl-prolyl isomerase CWC27

1

5

High-throughput

0.479

High

766949

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

1

High-throughput

0.479

High

766951

TAF12
Transcription initiation factor TFIID subunit 12

1

2

High-throughput

0.479

High

766974

YRA1
RNA annealing protein YRA1

1

5

High-throughput

0.479

High

766975

BBP
Branchpoint-bridging protein

1

3

Small-scale

0.479

High

469788

YSF3
RDS3 complex subunit 10

1

0

High-throughput

0.458

High

662329

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

664854

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

704349

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

748070

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

748142

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

766912

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

766916

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

766928

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

766932

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.458

High

766946

IMA1
Importin subunit alpha

1

0

High-throughput

0.458

High

766959

IMB1
Importin subunit beta-1

1

0

High-throughput

0.458

High

766968

PBP4
Protein PBP4

1

0

High-throughput

0.458

High

766983

MTR10
mRNA transport regulator MTR10

1

0

Small-scale

0.458

High

511450

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

766938

SEN1
Helicase SEN1

1

4

Small-scale

0.445

High

629336

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.426

High

753750

NEM1
Nuclear envelope morphology protein 1

1

0

High-throughput

0.282

High

766919

CCC1
Protein CCC1

1

0

High-throughput

0.265

Low

762231

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

766926

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

766964

CENPO
Inner kinetochore subunit MCM21

1

0

High-throughput

0.238

Low

760735

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024