Protein: GRIA2
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)

Gene: GRIA2
Organism: Mus musculus
Interactions: 175
UniProt ID: P23819

Gene Ontology (top 5):
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005234 - extracellularly glutamate-gated ion channel activity
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663018

GRIA1
Glutamate receptor 1

8

18

Small-scale

0.956

High

663202

GRIA3
Glutamate receptor 3

5

18

Small-scale

0.902

High

312690

CCG2
Voltage-dependent calcium channel gamma-2 subunit

3

15

Small-scale

0.827

High

663107

DLG4
Disks large homolog 4

7

20

Small-scale

0.737

High

663201

GRIA4
Glutamate receptor 4

2

18

Small-scale

0.737

High

104464

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

7

High-throughput

0.667

High

663177

DLGP1
Disks large-associated protein 1

3

7

High-throughput

0.656

High

663165

GRIP1
Glutamate receptor-interacting protein 1

3

20

Small-scale

0.643

High

663056

GRIA2
Glutamate receptor 2

1

18

High-throughput

0.618

High

663061

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

18

High-throughput

0.618

High

663062

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

18

High-throughput

0.618

High

663086

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

18

High-throughput

0.618

High

663191

CCG3
Voltage-dependent calcium channel gamma-3 subunit

1

15

High-throughput

0.618

High

663090

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

2

7

Small-scale

0.611

High

313246

NOE1
Noelin

2

1

Small-scale

0.584

High

663159

CCG8
Voltage-dependent calcium channel gamma-8 subunit

1

15

Small-scale

0.575

High

663098

SRC8
Src substrate cortactin

2

7

Small-scale

0.571

High

663083

TNIK
Traf2 and NCK-interacting protein kinase

1

7

High-throughput

0.536

High

598652

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

Small-scale

0.515

High

663194

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

Small-scale

0.513

High

60073

KALRN
Kalirin

1

14

High-throughput

0.489

High

73160

DLGP4
Disks large-associated protein 4

1

7

High-throughput

0.479

High

97359

PRRT2
Proline-rich transmembrane protein 2

1

1

High-throughput

0.479

High

97941

RYR2
Ryanodine receptor 2

1

6

High-throughput

0.479

High

204530

EXOC7
Exocyst complex component 7

1

2

Small-scale

0.479

High

204755

EXOC4
Exocyst complex component 4

1

3

Small-scale

0.479

High

266886

NPTX2
Neuronal pentraxin-2

1

1

Small-scale

0.479

High

503538

LRC4B
Leucine-rich repeat-containing protein 4B

1

3

High-throughput

0.479

High

556476

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

3

High-throughput

0.479

High

580346

CADH2
Cadherin-2

1

1

Small-scale

0.479

High

595021

KCNA1
Potassium voltage-gated channel subfamily A member 1

1

1

High-throughput

0.479

High

627454

BIP
Endoplasmic reticulum chaperone BiP

1

2

Small-scale

0.479

High

663060

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

4

High-throughput

0.479

High

663064

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

9

High-throughput

0.479

High

663068

NSF
Vesicle-fusing ATPase

1

4

Small-scale

0.479

High

663076

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

1

High-throughput

0.479

High

663081

STIM1
Stromal interaction molecule 1

1

5

High-throughput

0.479

High

663082

STIM2
Stromal interaction molecule 2

1

5

High-throughput

0.479

High

663084

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

1

High-throughput

0.479

High

663087

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

8

High-throughput

0.479

High

663089

SHSA6
Protein shisa-6

1

3

High-throughput

0.479

High

663096

DIRA2
GTP-binding protein Di-Ras2

1

5

High-throughput

0.479

High

663100

AKT2
RAC-beta serine/threonine-protein kinase

1

10

High-throughput

0.479

High

663101

SC6A4
Sodium-dependent serotonin transporter

1

4

High-throughput

0.479

High

663103

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

6

High-throughput

0.479

High

663105

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

High-throughput

0.479

High

663106

PICK1
PRKCA-binding protein

1

11

Small-scale

0.479

High

663111

SQSTM
Sequestosome-1

1

4

Small-scale

0.479

High

663116

RN220
E3 ubiquitin-protein ligase Rnf220

1

4

Small-scale

0.479

High

663117

DLGP3
Disks large-associated protein 3

1

7

High-throughput

0.479

High

663119

TAOK2
Serine/threonine-protein kinase TAO2

1

8

High-throughput

0.479

High

663130

SLIK5
SLIT and NTRK-like protein 5

1

5

High-throughput

0.479

High

663131

SVOP
Synaptic vesicle 2-related protein

1

1

High-throughput

0.479

High

663132

CPT1C
Palmitoyl thioesterase CPT1C

1

1

High-throughput

0.479

High

663135

DLGP2
Disks large-associated protein 2

1

7

High-throughput

0.479

High

663136

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

663140

LRC4C
Leucine-rich repeat-containing protein 4C

1

3

High-throughput

0.479

High

663141

TMX4
Thioredoxin-related transmembrane protein 4

1

1

High-throughput

0.479

High

663143

ELFN1
Protein ELFN1

1

5

High-throughput

0.479

High

663148

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

1

High-throughput

0.479

High

663151

KCNQ3
Potassium voltage-gated channel subfamily KQT member 3

1

6

High-throughput

0.479

High

663154

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.479

High

663158

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.479

High

663160

CSPG4
Chondroitin sulfate proteoglycan 4

1

4

Small-scale

0.479

High

663162

LNX2
Ligand of Numb protein X 2

1

20

High-throughput

0.479

High

663167

ABD12
Lysophosphatidylserine lipase ABHD12

1

1

High-throughput

0.479

High

663169

RTN4
Reticulon-4

1

2

High-throughput

0.479

High

663173

NRX1A
Neurexin-1

1

4

High-throughput

0.479

High

663175

SHSA9
Protein shisa-9

1

3

High-throughput

0.479

High

663176

RUFY3
Protein RUFY3

1

1

High-throughput

0.479

High

663179

SUN1
SUN domain-containing protein 1

1

5

High-throughput

0.479

High

663181

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

3

High-throughput

0.479

High

663186

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

1

High-throughput

0.479

High

663193

KCNQ5
Potassium voltage-gated channel subfamily KQT member 5

1

6

High-throughput

0.479

High

663198

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

663199

KCND3
A-type voltage-gated potassium channel KCND3

1

1

High-throughput

0.479

High

73138

FRS1L
DOMON domain-containing protein FRRS1L

1

0

High-throughput

0.458

High

266737

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.458

High

267229

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.458

High

312790

PCDA4
Protocadherin alpha-4

1

0

High-throughput

0.458

High

663057

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

663069

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.458

High

663070

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.458

High

663072

AQP4
Aquaporin-4

1

0

High-throughput

0.458

High

663073

CYB5
Cytochrome b5

1

0

High-throughput

0.458

High

663074

WFS1
Wolframin

1

0

High-throughput

0.458

High

663077

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

663091

PITM3
Membrane-associated phosphatidylinositol transfer protein 3

1

0

High-throughput

0.458

High

663095

VEZA
Vezatin

1

0

High-throughput

0.458

High

663114

RETR2
Reticulophagy regulator 2

1

0

High-throughput

0.458

High

663120

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

663121

PLPR4
Phospholipid phosphatase-related protein type 4

1

0

High-throughput

0.458

High

663124

ASTRB
Protein Aster-B

1

0

High-throughput

0.458

High

663126

PLXA4
Plexin-A4

1

0

Small-scale

0.458

High

663127

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

663128

C2C2L
Phospholipid transfer protein C2CD2L

1

0

High-throughput

0.458

High

663129

AGRB3
Adhesion G protein-coupled receptor B3

1

0

High-throughput

0.458

High

663133

REEP1
Receptor expression-enhancing protein 1

1

0

High-throughput

0.458

High

663137

NCS1
Neuronal calcium sensor 1

1

0

High-throughput

0.458

High

663139

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

663142

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

663144

CNST
Consortin

1

0

High-throughput

0.458

High

663146

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.458

High

663150

HACD3
Very-long-chain

1

0

High-throughput

0.458

High

663152

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

0

High-throughput

0.458

High

663153

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

0

High-throughput

0.458

High

663161

SFPQ
Splicing factor, proline- and glutamine-rich

1

0

High-throughput

0.458

High

663163

SYUB
Beta-synuclein

1

0

High-throughput

0.458

High

663166

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.458

High

663172

TXD12
Thioredoxin domain-containing protein 12

1

0

High-throughput

0.458

High

663182

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

663183

TMM43
Transmembrane protein 43

1

0

High-throughput

0.458

High

663187

KCNH7
Voltage-gated inwardly rectifying potassium channel KCNH7

1

0

High-throughput

0.458

High

663188

JPH3
Junctophilin-3

1

0

High-throughput

0.458

High

663190

PROF2
Profilin-2

1

0

High-throughput

0.458

High

593883

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

2

Small-scale

0.445

High

663079

ACTG
Actin, cytoplasmic 2

1

4

Small-scale

0.445

High

663178

ATAD1
Outer mitochondrial transmembrane helix translocase

1

1

Small-scale

0.445

High

147622

EMD
Emerin

1

1

High-throughput

0.437

High

663058

H2AX
Histone H2AX

1

1

High-throughput

0.437

High

663063

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.437

High

663065

NCPR
NADPH--cytochrome P450 reductase

1

2

High-throughput

0.437

High

663092

CDKL5
Cyclin-dependent kinase-like 5

1

4

High-throughput

0.437

High

663097

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

2

High-throughput

0.437

High

663102

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.437

High

663108

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

663113

EXOC3
Exocyst complex component 3

1

1

Small-scale

0.437

High

663115

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.437

High

663125

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.437

High

663134

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

5

High-throughput

0.437

High

663145

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

1

High-throughput

0.437

High

663155

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.437

High

663168

ACL6B
Actin-like protein 6B

1

5

High-throughput

0.437

High

663170

RRBP1
Ribosome-binding protein 1

1

6

High-throughput

0.437

High

663180

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

1

High-throughput

0.437

High

663185

AT131
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.437

High

663192

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

1

High-throughput

0.437

High

663195

KC1E
Casein kinase I isoform epsilon

1

5

High-throughput

0.437

High

663196

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.437

High

663059

GRN
Progranulin

1

0

Small-scale

0.426

High

663066

HSPA9
Stress-70 protein, mitochondrial

1

3

Small-scale

0.407

High

663080

TBA1C
Tubulin alpha-1C chain

1

6

Small-scale

0.407

High

663085

TBB5
Tubulin beta-5 chain

1

3

Small-scale

0.407

High

92639

SAFB1
Scaffold attachment factor B1

1

0

High-throughput

0.249

Low

312250

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low

360498

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.249

Low

361942

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.249

Low

663067

H14
Histone H1.4

1

0

High-throughput

0.249

Low

663071

FABP7
Fatty acid-binding protein, brain

1

0

High-throughput

0.249

Low

663075

H4
Histone H4

1

0

High-throughput

0.249

Low

663078

TRA2B
Transformer-2 protein homolog beta

1

0

High-throughput

0.249

Low

663088

OSBP1
Oxysterol-binding protein 1

1

0

High-throughput

0.249

Low

663093

F91A1
Protein FAM91A1

1

0

High-throughput

0.249

Low

663094

Q3UZG4
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

1

0

High-throughput

0.249

Low

663104

NPM
Nucleophosmin

1

0

High-throughput

0.249

Low

663109

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

663110

CYTB
Cystatin-B

1

0

High-throughput

0.249

Low

663112

TMCC1
Transmembrane and coiled-coil domains protein 1

1

0

High-throughput

0.249

Low

663118

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

663122

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

663123

PR38B
Pre-mRNA-splicing factor 38B

1

0

High-throughput

0.249

Low

663138

F177A
Protein FAM177A1

1

0

High-throughput

0.249

Low

663147

H2B1P
Histone H2B type 1-P

1

0

High-throughput

0.249

Low

663149

STX5
Syntaxin-5

1

0

High-throughput

0.249

Low

663156

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.249

Low

663157

MICU1
Calcium uptake protein 1, mitochondrial

1

0

High-throughput

0.249

Low

663164

LRC59
Leucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]

1

0

High-throughput

0.249

Low

663171

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.249

Low

663174

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.249

Low

663184

CRIP2
Cysteine-rich protein 2

1

0

High-throughput

0.249

Low

663189

TACC2
Transforming acidic coiled-coil-containing protein 2

1

0

High-throughput

0.249

Low

663197

SEC12
Guanine nucleotide-exchange factor SEC12

1

0

High-throughput

0.249

Low

663200

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.249

Low

663099

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025