Protein: METK1
S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1) (Methionine adenosyltransferase I/III) (MAT-I/III)

Gene: METK1, MAT1A
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q00266

Gene Ontology (top 5):
GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006556 - S-adenosylmethionine biosynthetic process
GO:0006730 - one-carbon metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678612

METK2
S-adenosylmethionine synthase isoform type-2

5

16

High-throughput

0.926

High

959169

METK1
S-adenosylmethionine synthase isoform type-1

3

15

High-throughput

0.861

High

959177

MAT2B
Methionine adenosyltransferase 2 subunit beta

3

1

High-throughput

0.861

High

959175

ASPC1
Tether containing UBX domain for GLUT4

3

0

High-throughput

0.638

High

394541

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

791485

HD
Huntingtin

1

0

High-throughput

0.493

High

959170

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

959171

DCAF6
DDB1- and CUL4-associated factor 6

1

2

High-throughput

0.479

High

959178

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

828985

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

379297

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

959173

RHG24
Rho GTPase-activating protein 24

1

4

High-throughput

0.437

High

959176

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

959172

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.279

Low

959174

TECTB
Beta-tectorin

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024