Protein: SRB8
Mediator of RNA polymerase II transcription subunit 12 (Mediator complex subunit 12) (Suppressor of RNA polymerase B 8)

Gene: SRB8
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P25648

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000411 - positive regulation of transcription by galactose
GO:0003713 - transcription coactivator activity
GO:0016592 - mediator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635996

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

6

7

Small-scale

0.735

High

635993

SSN3
Meiotic mRNA stability protein kinase SSN3

6

6

Small-scale

0.733

High

636002

MED7
Mediator of RNA polymerase II transcription subunit 7

4

3

Small-scale

0.691

High

635992

SSN2
Mediator of RNA polymerase II transcription subunit 13

5

0

Small-scale

0.684

High

581338

MED14
Mediator of RNA polymerase II transcription subunit 14

3

3

Small-scale

0.660

High

626011

MED19
Mediator of RNA polymerase II transcription subunit 19

4

0

Small-scale

0.654

High

635991

MED31
Mediator of RNA polymerase II transcription subunit 31

3

3

High-throughput

0.643

High

636005

MED1
Mediator of RNA polymerase II transcription subunit 1

3

0

Small-scale

0.632

High

635998

MED5
Mediator of RNA polymerase II transcription subunit 5

3

0

Small-scale

0.628

High

636003

MED2
Mediator of RNA polymerase II transcription subunit 2

3

0

High-throughput

0.616

High

635984

MED18
Mediator of RNA polymerase II transcription subunit 18

3

0

Small-scale

0.613

High

635983

MED22
Mediator of RNA polymerase II transcription subunit 22

2

0

High-throughput

0.595

High

636000

MED10
Mediator of RNA polymerase II transcription subunit 10

2

2

Small-scale

0.595

High

635980

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.585

High

635997

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.576

High

635982

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

Small-scale

0.559

High

635994

MED3
Mediator of RNA polymerase II transcription subunit 3

2

0

Small-scale

0.547

High

493325

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.504

High

635986

PDR3
Transcription factor PDR3

1

0

Small-scale

0.458

High

635987

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.458

High

635989

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

636006

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

635999

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

490487

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

510433

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

635981

PRP21
Pre-mRNA-splicing factor PRP21

1

0

High-throughput

0.265

Low

381528

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.251

Low

543293

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

619411

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

620611

EXG1
Glucan 1,3-beta-glucosidase I/II

1

0

High-throughput

0.249

Low

635979

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

635985

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

635988

TTI1
TEL2-interacting protein 1

1

0

High-throughput

0.249

Low

635990

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.249

Low

635995

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

636001

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

539525

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

636004

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024