HitPredict - High confidence protein-protein interactions

Protein: HG2A
H-2 class II histocompatibility antigen gamma chain (Ia antigen-associated invariant chain) (Ii) (Ii chain) (MHC class II-associated invariant chain) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]

Gene: HG2A, Cd74
Organism: Mus musculus
Interactions: 6
UniProt ID: P04441

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0001540 - amyloid-beta binding
GO:0001961 - positive regulation of cytokine-mediated signaling pathway
GO:0002606 - positive regulation of dendritic cell antigen processing and presentation
GO:0002792 - negative regulation of peptide secretion

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
409632	HA2U H-2 class II histocompatibility antigen, A-U alpha chain	1	9	Small-scale	0.618	High
409633	HB2J H-2 class II histocompatibility antigen, I-E beta chain	1	8	Small-scale	0.618	High
409634	IRF8 Interferon regulatory factor 8	1	1	High-throughput	0.479	High
409636	TRI59 Tripartite motif-containing protein 59	1	0	Small-scale	0.460	High
409631	EGR2 E3 SUMO-protein ligase EGR2	1	0	Small-scale	0.458	High
409635	EAA2 Excitatory amino acid transporter 2	1	0	Small-scale	0.458	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025