Interactor 1: HG2A (P04441)
H-2 class II histocompatibility antigen gamma chain (Ia antigen-associated invariant chain) (Ii) (Ii chain) (MHC class II-associated invariant chain) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: Cd74

Interactor 2: HA2U (P14438)
H-2 class II histocompatibility antigen, A-U alpha chain
Gene: H2-Aa

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16242130
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~MHC2-interact, MHC2-interact~MHC_II_alpha
Common GO terms GO:0005764 - lysosome
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0019882 - antigen processing and presentation
GO:0019886 - antigen processing and presentation of exogenous peptide antigen via MHC class II
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 279
Mm

1 227
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025