Protein: EGR2
E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20)

Gene: EGR2
Organism: Mus musculus
Interactions: 58
UniProt ID: P08152

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

466719

EGR2
E3 SUMO-protein ligase EGR2

1

17

Small-scale

0.618

High

466736

REPI1
DNA-binding protein REPIN1

1

11

Small-scale

0.618

High

466738

NAB2
NGFI-A-binding protein 2

2

6

Small-scale

0.565

High

466731

CRTAM
Cytotoxic and regulatory T-cell molecule

1

1

Small-scale

0.553

High

466751

ST32C
Serine/threonine-protein kinase 32C

1

3

Small-scale

0.553

High

466765

FPRP
Prostaglandin F2 receptor negative regulator

1

3

Small-scale

0.553

High

466726

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.552

High

466748

PIAS2
E3 SUMO-protein ligase PIAS2

1

1

Small-scale

0.543

High

148522

CYH3
Cytohesin-3

1

1

Small-scale

0.479

High

204500

TNF11
Tumor necrosis factor ligand superfamily member 11

1

5

Small-scale

0.479

High

266979

FHL2
Four and a half LIM domains protein 2

1

13

Small-scale

0.479

High

312000

TTC3
E3 ubiquitin-protein ligase TTC3

1

2

Small-scale

0.479

High

373662

MYC
Myc proto-oncogene protein

1

9

Small-scale

0.479

High

466722

RABP2
Cellular retinoic acid-binding protein 2

1

1

Small-scale

0.479

High

466724

TSN5
Tetraspanin-5

1

1

Small-scale

0.479

High

466727

BACH2
Transcription regulator protein BACH2

1

7

Small-scale

0.479

High

466728

SOX8
Transcription factor SOX-8

1

17

Small-scale

0.479

High

466732

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

4

Small-scale

0.479

High

466734

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

4

Small-scale

0.479

High

466739

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

1

Small-scale

0.479

High

466744

DGKZ
Diacylglycerol kinase zeta

1

3

Small-scale

0.479

High

466753

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

1

Small-scale

0.479

High

466755

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

Small-scale

0.479

High

466757

RAI14
Ankycorbin

1

4

Small-scale

0.479

High

466760

RFOX1
RNA binding protein fox-1 homolog 1

1

2

Small-scale

0.479

High

466766

CIB2
Calcium and integrin-binding family member 2

1

1

Small-scale

0.479

High

236677

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.458

High

409631

HG2A
H-2 class II histocompatibility antigen gamma chain

1

0

Small-scale

0.458

High

466725

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

0

Small-scale

0.458

High

466733

ECE1
Endothelin-converting enzyme 1

1

0

Small-scale

0.458

High

466742

DDX11
ATP-dependent DNA helicase DDX11

1

0

Small-scale

0.458

High

466743

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

0

Small-scale

0.458

High

466745

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

Small-scale

0.458

High

466750

CAH12
Carbonic anhydrase 12

1

0

Small-scale

0.458

High

466754

MCRI2
MAPK regulated corepressor interacting protein 2

1

0

Small-scale

0.458

High

466756

RGCC
Regulator of cell cycle RGCC

1

0

Small-scale

0.458

High

466761

PDK2
[Pyruvate dehydrogenase

1

0

Small-scale

0.458

High

466763

ARL3
ADP-ribosylation factor-like protein 3

1

0

Small-scale

0.458

High

466737

NAB1
NGFI-A-binding protein 1

1

6

Small-scale

0.457

High

97816

RYR1
Ryanodine receptor 1

1

3

Small-scale

0.437

High

466720

CCL1
C-C motif chemokine 1

1

1

Small-scale

0.437

High

466721

TNR9
Tumor necrosis factor receptor superfamily member 9

1

6

Small-scale

0.437

High

466729

PROS
Vitamin K-dependent protein S

1

16

Small-scale

0.437

High

466741

CISH
Cytokine-inducible SH2-containing protein

1

5

Small-scale

0.437

High

466747

K1958
Uncharacterized protein KIAA1958 homolog

1

7

Small-scale

0.437

High

466762

SEM7A
Semaphorin-7A

1

1

Small-scale

0.437

High

312734

PAR4
Proteinase-activated receptor 4

1

3

Small-scale

0.417

High

466723

NEUG
Neurogranin

1

0

Small-scale

0.249

Low

466730

EXPH5
Exophilin-5

1

0

Small-scale

0.249

Low

466735

D39U1
Epimerase family protein SDR39U1

1

0

Small-scale

0.249

Low

466740

LAG3
Lymphocyte activation gene 3 protein

1

0

Small-scale

0.249

Low

466746

VGLU2
Vesicular glutamate transporter 2

1

0

Small-scale

0.249

Low

466749

NRN1
Neuritin

1

0

Small-scale

0.249

Low

466752

S13A3
Na(+)/dicarboxylate cotransporter 3

1

0

Small-scale

0.249

Low

466758

OLR1
Oxidized low-density lipoprotein receptor 1

1

0

Small-scale

0.249

Low

466759

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

Small-scale

0.249

Low

466764

ARC
Activity-regulated cytoskeleton-associated protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025