Protein: TPMT
Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase)

Gene: TPMT
Organism: Homo sapiens
Interactions: 11
UniProt ID: P51580

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006139 - nucleobase-containing compound metabolic process
GO:0006805 - xenobiotic metabolic process
GO:0008119 - thiopurine S-methyltransferase activity
GO:0032259 - methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

904249

1433G
14-3-3 protein gamma

1

0

High-throughput

0.493

High

904251

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.493

High

421751

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

872091

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

904250

SRSF1
Serine/arginine-rich splicing factor 1

1

0

High-throughput

0.279

Low

904254

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.279

Low

904256

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.279

Low

506930

POTEI
POTE ankyrin domain family member I

1

0

High-throughput

0.269

Low

904252

USPL1
SUMO-specific isopeptidase USPL1

1

0

High-throughput

0.269

Low

904255

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low

904253

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025