Protein: USPL1
SUMO-specific isopeptidase USPL1 (EC 3.4.22.-) (Ubiquitin-specific peptidase-like protein 1) (USP-like 1)

Gene: USPL1
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q5W0Q7

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0008283 - cell population proliferation
GO:0009301 - snRNA transcription
GO:0015030 - Cajal body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

939197

SUMO3
Small ubiquitin-related modifier 3

3

2

Small-scale

0.793

High

964323

SUMO2
Small ubiquitin-related modifier 2

2

2

Small-scale

0.735

High

991347

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.677

High

1219918

EAF1
ELL-associated factor 1

2

0

High-throughput

0.602

High

936598

ELL
RNA polymerase II elongation factor ELL

2

0

Small-scale

0.585

High

1007520

KRT85
Keratin, type II cuticular Hb5

1

1

High-throughput

0.536

High

402946

ANXA1
Annexin A1

1

0

High-throughput

0.513

High

552987

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

553208

KCRB
Creatine kinase B-type

1

0

High-throughput

0.513

High

1219922

ICE1
Little elongation complex subunit 1

1

0

High-throughput

0.513

High

618146

K2C4
Keratin, type II cytoskeletal 4

1

1

High-throughput

0.407

High

854670

RAGP1
Ran GTPase-activating protein 1

2

0

Small-scale

0.314

High

890839

TSC2
Tuberin

1

0

High-throughput

0.282

High

720884

KPYR
Pyruvate kinase PKLR

1

0

High-throughput

0.279

Low

749928

KINH
Kinesin-1 heavy chain

1

0

High-throughput

0.279

Low

909043

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.279

Low

910313

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.279

Low

1211252

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.279

Low

1219921

ANFY1
Rabankyrin-5

1

0

High-throughput

0.279

Low

904252

TPMT
Thiopurine S-methyltransferase

1

0

High-throughput

0.269

Low

659244

SP100
Nuclear autoantigen Sp-100

1

0

Small-scale

0.261

Low

239442

PLIN1
Perilipin-1

1

0

High-throughput

0.249

Low

271328

ZBED4
Zinc finger BED domain-containing protein 4

1

0

High-throughput

0.249

Low

460559

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.249

Low

772850

MYH9
Myosin-9

1

0

High-throughput

0.249

Low

1068230

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.249

Low

1219919

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.249

Low

1219923

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.249

Low

1219924

TRI17
E3 ubiquitin-protein ligase TRIM17

1

0

Small-scale

0.249

Low

1219920

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025