Protein: SIR1
Regulatory protein SIR1 (Heterochromatin protein SIR1) (Silent information regulator 1)

Gene: SIR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 21
UniProt ID: P21691

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0003682 - chromatin binding
GO:0005677 - chromatin silencing complex
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031507 - heterochromatin formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600276

ORC1
Origin recognition complex subunit 1

7

1

Small-scale

0.972

High

416281

SIR3
Regulatory protein SIR3

3

1

Small-scale

0.860

High

516845

SIR4
Regulatory protein SIR4

6

0

Small-scale

0.696

High

600279

RLF2
Chromatin assembly factor 1 subunit p90

1

0

Small-scale

0.561

High

600273

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.504

High

416192

SIR2
NAD-dependent histone deacetylase SIR2

1

0

Small-scale

0.493

High

510258

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.489

High

600268

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.458

High

600277

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

490336

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

493199

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

600267

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

514612

FUS1
Nuclear fusion protein FUS1

2

0

High-throughput

0.323

High

600280

YC021
Putative uncharacterized protein YCL021W-A

1

0

High-throughput

0.282

High

600269

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.279

Low

600272

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

600275

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.249

Low

600278

CDC14
Tyrosine-protein phosphatase CDC14

1

0

Small-scale

0.249

Low

600270

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low

600271

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low

600274

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024