Protein: NPC1
NPC intracellular sterol transporter 1-related protein 1 (Niemann-Pick type C-related protein 1)

Gene: NPC1, NCR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q12200

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0006665 - sphingolipid metabolic process
GO:0015485 - cholesterol binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

704091

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

2

High-throughput

0.582

High

771503

CYB5
Cytochrome b5

1

1

Small-scale

0.552

High

693513

SNQ2
Protein SNQ2

1

2

High-throughput

0.541

High

757930

ATC2
Calcium-transporting ATPase 2

1

5

High-throughput

0.541

High

715535

SC61G
Protein transport protein SSS1

1

0

Small-scale

0.529

High

976997

LIP1
Ceramide synthase subunit LIP1

1

0

Small-scale

0.529

High

1014915

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

High-throughput

0.518

High

541821

SEC63
Protein translocation protein SEC63

1

5

Small-scale

0.481

High

701624

SC61A
Protein transport protein SEC61

1

2

Small-scale

0.481

High

749061

SSH1
Sec sixty-one protein homolog

1

2

Small-scale

0.481

High

752784

LAG1
Ceramide synthase LAG1

1

2

Small-scale

0.481

High

777352

HACD
Very-long-chain

1

1

Small-scale

0.481

High

783544

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

Small-scale

0.481

High

856964

SC6B1
Protein transport protein SBH1

1

1

Small-scale

0.481

High

856973

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.481

High

1015307

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

3

Small-scale

0.481

High

1015306

NPC2
Phosphatidylglycerol/phosphatidylinositol transfer protein

1

0

Small-scale

0.480

High

513520

PPB
Repressible alkaline phosphatase

1

1

High-throughput

0.479

High

630622

ADP1
Probable ATP-dependent permease

1

3

High-throughput

0.479

High

689025

VA0D
V-type proton ATPase subunit d

1

1

High-throughput

0.479

High

693247

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

4

High-throughput

0.479

High

797360

VTC2
Vacuolar transporter chaperone complex subunit 2

1

4

High-throughput

0.479

High

811300

VTC4
Vacuolar transporter chaperone complex subunit 4

1

4

High-throughput

0.479

High

822955

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

972051

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

4

High-throughput

0.479

High

749138

YSY6
Protein YSY6

1

0

Small-scale

0.460

High

649004

PHO91
Low-affinity phosphate transporter PHO91

1

0

High-throughput

0.458

High

689451

YBT1
ATP-dependent bile acid permease

1

0

High-throughput

0.458

High

696835

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.458

High

731446

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.458

High

758521

VTC5
Vacuole transporter chaperone complex subunit 5

1

0

High-throughput

0.458

High

698137

YSC84
Protein YSC84

1

1

High-throughput

0.457

High

797876

LSB3
LAS seventeen-binding protein 3

1

1

High-throughput

0.457

High

513172

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

769783

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

1015216

PSH1
RING finger protein PSH1

1

1

Small-scale

0.439

High

663651

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

696101

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.407

High

859894

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

416819

CDC31
Cell division control protein 31

1

0

High-throughput

0.249

Low

634502

PEX34
Peroxisomal membrane protein PEX34

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024