Protein: GSP
Bifunctional glutathionylspermidine synthetase/amidase (GspSA) [Includes: Glutathionylspermidine amidase (Gsp amidase) (EC 3.5.1.78) (Glutathionylspermidine amidohydrolase [spermidine-forming]); Glutathionylspermidine synthetase (Gsp synthetase) (EC 6.3.1.8) (Glutathione:spermidine ligase [ADP-forming]) (Gsp synthase)]

Gene: GSP, gss
Organism: Escherichia coli K-12
Interactions: 14
UniProt ID: P0AES0

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006749 - glutathione metabolic process
GO:0008216 - spermidine metabolic process
GO:0008884 - glutathionylspermidine amidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

500403

RHO
Transcription termination factor Rho

3

0

High-throughput

0.647

High

500409

YIIM
Protein YiiM

1

0

High-throughput

0.518

High

494885

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.513

High

500404

KATG
Catalase-peroxidase

1

0

High-throughput

0.513

High

500406

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

500412

HPRS
Sensor histidine kinase HprS

1

0

High-throughput

0.513

High

500408

FIXB
Protein FixB

1

0

High-throughput

0.304

High

500411

YJIM
Putative dehydratase subunit YjiM

1

0

High-throughput

0.282

High

432390

PTHA
PTS system glucitol/sorbitol-specific EIIA component

1

0

High-throughput

0.279

Low

496152

BAMA
Outer membrane protein assembly factor BamA

1

0

High-throughput

0.279

Low

500405

CHIA
Probable bifunctional chitinase/lysozyme [Includes: Chitinase

1

0

High-throughput

0.279

Low

500410

RSPA
Starvation-sensing protein RspA

1

0

High-throughput

0.279

Low

500413

ECPB
Probable fimbrial chaperone EcpB

1

0

High-throughput

0.279

Low

500407

DKGB
Methylglyoxal reductase DkgB

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025