Protein: TGT
Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)

Gene: TGT
Organism: Escherichia coli K-12
Interactions: 40
UniProt ID: P0A847

Gene Ontology (top 5):
GO:0002099 - tRNA wobble guanine modification
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0008479 - tRNA-guanosine(34) queuine transglycosylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

494884

DBHB
DNA-binding protein HU-beta

2

1

High-throughput

0.588

High

395142

UVRD
DNA helicase II

2

0

High-throughput

0.563

High

490863

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.563

High

492341

RF3
Peptide chain release factor RF3

2

0

High-throughput

0.563

High

492461

RL7
Large ribosomal subunit protein bL12

2

0

High-throughput

0.563

High

492816

RL20
Large ribosomal subunit protein bL20

2

0

High-throughput

0.563

High

492891

RL28
Large ribosomal subunit protein bL28

2

0

High-throughput

0.563

High

493129

RL9
Large ribosomal subunit protein bL9

2

0

High-throughput

0.563

High

493321

RS12
Small ribosomal subunit protein uS12

2

0

High-throughput

0.563

High

494783

SSRP
SsrA-binding protein

2

0

High-throughput

0.563

High

494881

DEAD
ATP-dependent RNA helicase DeaD

2

0

High-throughput

0.563

High

494889

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.563

High

494899

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.563

High

489499

CH60
Chaperonin GroEL

1

1

High-throughput

0.536

High

477736

MASY
Malate synthase A

1

0

High-throughput

0.513

High

494885

GSP
Bifunctional glutathionylspermidine synthetase/amidase

1

0

High-throughput

0.513

High

494892

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

449824

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

1

High-throughput

0.484

High

492684

RL1
Large ribosomal subunit protein uL1

1

1

High-throughput

0.484

High

494883

DBHA
DNA-binding protein HU-alpha

1

1

High-throughput

0.484

High

494893

RNR
Ribonuclease R

1

1

High-throughput

0.484

High

382649

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.464

High

492571

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

494229

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.464

High

494880

RPOB
DNA-directed RNA polymerase subunit beta

1

0

High-throughput

0.464

High

494882

RL13
Large ribosomal subunit protein uL13

1

0

High-throughput

0.464

High

494886

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.464

High

494887

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.464

High

494888

RL21
Large ribosomal subunit protein bL21

1

0

High-throughput

0.464

High

494890

RS1
Small ribosomal subunit protein bS1

1

0

High-throughput

0.464

High

494891

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

High-throughput

0.464

High

494895

RLUB
Ribosomal large subunit pseudouridine synthase B

1

0

High-throughput

0.464

High

494896

RL2
Large ribosomal subunit protein uL2

1

0

High-throughput

0.464

High

494897

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.464

High

494898

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.464

High

494900

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

494901

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

0

High-throughput

0.464

High

494894

BCSA
Cellulose synthase catalytic subunit [UDP-forming]

2

0

High-throughput

0.307

High

494902

INTE
Prophage integrase IntE

1

0

High-throughput

0.279

Low

494903

RSXG
Ion-translocating oxidoreductase complex subunit G

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025