HitPredict - High confidence protein-protein interactions

Protein: FCGR2
Low affinity immunoglobulin gamma Fc region receptor II (Fc gamma receptor IIB) (Fc-gamma RII) (Fc-gamma-RIIB) (FcRII) (IgG Fc receptor II beta) (Lymphocyte antigen 17) (Ly-17) (CD antigen CD32)

Gene: FCGR2
Organism: Mus musculus
Interactions: 6
UniProt ID: P08101

Gene Ontology (top 5):
GO:0001811 - negative regulation of type I hypersensitivity
GO:0002638 - negative regulation of immunoglobulin production
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0002865 - negative regulation of acute inflammatory response to antigenic stimulus
GO:0002924 - negative regulation of humoral immune response mediated by circulating immunoglobulin

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
465761	Q3UCL2 E3 ubiquitin-protein ligase TRIM21	1	2	Small-scale	0.561	High
465762	UBP7 Ubiquitin carboxyl-terminal hydrolase 7	1	3	High-throughput	0.479	High
465764	SHIP1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	1	9	Small-scale	0.445	High
465763	TRI33 E3 ubiquitin-protein ligase TRIM33	1	4	Small-scale	0.437	High
465760	DOK1 Docking protein 1	1	0	Small-scale	0.261	Low
465759	SPI1 Transcription factor PU.1	1	0	Small-scale	0.249	Low

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Last updated: 11Aug2025