HitPredict - High confidence protein-protein interactions

Protein: FOLC
Dihydrofolate synthase/folylpolyglutamate synthase (DHFS / FPGS) (EC 6.3.2.12) (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase) (Folylpolyglutamate synthetase) (Tetrahydrofolylpolyglutamate synthase)

Gene: FOLC
Organism: Escherichia coli K-12
Interactions: 9
UniProt ID: P08192

Gene Ontology (top 5):
GO:0004326 - tetrahydrofolylpolyglutamate synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006730 - one-carbon metabolic process
GO:0006761 - dihydrofolate biosynthetic process

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
467323	DNAK Chaperone protein DnaK	1	3	High-throughput	0.536	High
467326	NADE NH(3)-dependent NAD(+) synthetase	1	3	High-throughput	0.536	High
467324	TRPB Tryptophan synthase beta chain	1	0	High-throughput	0.513	High
467327	SYD Aspartate--tRNA ligase	1	0	High-throughput	0.513	High
467328	LHR Lhr helicase/uracil glycosylase	1	0	High-throughput	0.513	High
467331	YKFG UPF0758 protein YkfG	1	0	High-throughput	0.513	High
467330	YNFF Probable dimethyl sulfoxide reductase chain YnfF	2	0	High-throughput	0.310	High
467325	UIDR HTH-type transcriptional regulator UidR	1	0	High-throughput	0.279	Low
467329	BGLX Periplasmic beta-glucosidase	1	0	High-throughput	0.279	Low

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Last updated: 11Aug2025