Protein: SYD
Aspartate--tRNA ligase (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS)

Gene: SYD, aspS
Organism: Escherichia coli K-12
Interactions: 31
UniProt ID: P21889

Gene Ontology (top 5):
GO:0003676 - nucleic acid binding
GO:0004815 - aspartate-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006422 - aspartyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495517

SYN
Asparagine--tRNA ligase

1

14

High-throughput

0.691

High

641732

SYD
Aspartate--tRNA ligase

1

13

High-throughput

0.618

High

616845

NADE
NH(3)-dependent NAD(+) synthetase

2

1

High-throughput

0.611

High

494629

RPOA
DNA-directed RNA polymerase subunit alpha

2

0

High-throughput

0.563

High

486851

GLTD
Glutamate synthase [NADPH] small chain

1

3

High-throughput

0.536

High

491992

PFKA
ATP-dependent 6-phosphofructokinase isozyme 1

1

1

High-throughput

0.536

High

495838

RPOC
DNA-directed RNA polymerase subunit beta'

1

1

High-throughput

0.536

High

641735

ACNB
Aconitate hydratase B

1

2

High-throughput

0.536

High

395088

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.513

High

467327

FOLC
Dihydrofolate synthase/folylpolyglutamate synthase

1

0

High-throughput

0.513

High

492392

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

496803

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.513

High

641734

DGOK
2-dehydro-3-deoxygalactonokinase

1

0

High-throughput

0.513

High

641736

SGBE
L-ribulose-5-phosphate 4-epimerase SgbE

1

0

High-throughput

0.513

High

491442

IF2
Translation initiation factor IF-2

1

10

High-throughput

0.500

High

421041

FUMC
Fumarate hydratase class II

1

2

High-throughput

0.489

High

500392

GCL
Glyoxylate carboligase

1

1

High-throughput

0.489

High

491144

DNAK
Chaperone protein DnaK

1

3

Small-scale

0.479

High

641738

UPPS
Ditrans,polycis-undecaprenyl-diphosphate synthase

1

0

High-throughput

0.458

High

393895

PBPA
Penicillin-binding protein 1A

1

1

High-throughput

0.437

High

420131

FLIC
Flagellin

1

0

High-throughput

0.279

Low

491788

MOAC
Cyclic pyranopterin monophosphate synthase

1

0

High-throughput

0.279

Low

496678

NAPD
Chaperone NapD

1

0

High-throughput

0.279

Low

498411

CORA
Magnesium transport protein CorA

1

0

High-throughput

0.279

Low

498544

DNAG
DNA primase

1

0

High-throughput

0.279

Low

641733

NOHA
Prophage DNA-packing protein NohA

1

0

High-throughput

0.279

Low

641737

YCHO
Uncharacterized protein YchO

1

0

High-throughput

0.279

Low

641739

YAHG
Uncharacterized protein YahG

1

0

High-throughput

0.279

Low

641740

YDJF
Uncharacterized HTH-type transcriptional regulator YdjF

1

0

High-throughput

0.279

Low

641741

PERR
HTH-type transcriptional regulator PerR

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025