Protein: HIS5
Imidazole glycerol phosphate synthase hisHF (IGP synthase) (IGPS) (ImGP synthase) (EC 4.3.2.10) [Includes: Glutaminase (EC 3.5.1.2); Cyclase]

Gene: HIS5, HIS7
Organism: Saccharomyces cerevisiae S288C
Interactions: 15
UniProt ID: P33734

Gene Ontology (top 5):
GO:0000105 - L-histidine biosynthetic process
GO:0000107 - imidazoleglycerol-phosphate synthase activity
GO:0004359 - glutaminase activity
GO:0005737 - cytoplasm
GO:0016829 - lyase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

754137

DUS3
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]

1

0

High-throughput

0.493

High

754135

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

481570

HSP73
Heat shock protein SSA3

1

1

High-throughput

0.445

High

526305

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

754133

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

675869

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

752076

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

754134

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

602093

SPO16
Sporulation-specific protein 16

1

0

Small-scale

0.249

Low

706668

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

754132

RKM3
Ribosomal lysine N-methyltransferase 3

1

0

High-throughput

0.249

Low

754136

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

754138

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

0

High-throughput

0.249

Low

754139

PPT2
Mitochondrial holo-[acyl-carrier-protein] synthase

1

0

High-throughput

0.249

Low

754140

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025