HitPredict - High confidence protein-protein interactions

Protein: ISPH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (HMBPP reductase) (EC 1.17.7.4) (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase)

Gene: ISPH
Organism: Escherichia coli K-12
Interactions: 7
UniProt ID: P62623

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0016114 - terpenoid biosynthetic process
GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0046872 - metal ion binding
GO:0050992 - dimethylallyl diphosphate biosynthetic process

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Category	Interaction Score	Confidence
489920	CH60 Chaperonin GroEL	2	High-throughput	0.563	High
491239	DNAK Chaperone protein DnaK	1	High-throughput	0.493	High
492553	RL7 Large ribosomal subunit protein bL12	1	High-throughput	0.464	High
953320	RL4 Large ribosomal subunit protein uL4	1	High-throughput	0.464	High
492173	PTH Peptidyl-tRNA hydrolase	2	High-throughput	0.307	High
704192	YHDJ DNA adenine methyltransferase YhdJ	1	High-throughput	0.282	High
976953	FETA Probable iron export ATP-binding protein FetA	1	High-throughput	0.282	High

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Last updated: 11Aug2025