Protein: RL7
Large ribosomal subunit protein bL12 (50S ribosomal protein L7/L12) (L8)

Gene: RL7, rplL
Organism: Escherichia coli K-12
Interactions: 145
UniProt ID: P0A7K2

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003729 - mRNA binding
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492540

CSPB
Cold shock-like protein CspB

2

5

High-throughput

0.601

High

365803

RPOD
RNA polymerase sigma factor RpoD

2

1

High-throughput

0.588

High

492467

RPOB
DNA-directed RNA polymerase subunit beta

2

1

High-throughput

0.588

High

492473

CSPA
Cold shock protein CspA

2

5

High-throughput

0.588

High

492474

RLUC
Ribosomal large subunit pseudouridine synthase C

2

2

High-throughput

0.588

High

492483

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

2

1

High-throughput

0.588

High

492502

TSAE
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE

2

1

High-throughput

0.588

High

492509

RPOH
RNA polymerase sigma factor RpoH

2

1

High-throughput

0.588

High

492514

SELB
Selenocysteine-specific elongation factor

2

4

High-throughput

0.588

High

492516

HELD
DNA helicase IV

2

1

High-throughput

0.588

High

492547

OBG
GTPase ObgE/CgtA

2

3

High-throughput

0.588

High

492565

YDJI
Uncharacterized protein YdjI

2

1

High-throughput

0.588

High

492535

MOAD
Molybdopterin synthase sulfur carrier subunit

2

0

High-throughput

0.585

High

492559

YCCU
Uncharacterized protein YccU

2

0

High-throughput

0.585

High

492510

SSB
Single-stranded DNA-binding protein

2

1

High-throughput

0.584

High

492496

RL23
Large ribosomal subunit protein uL23

2

0

High-throughput

0.576

High

492503

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.576

High

492523

MUKB
Chromosome partition protein MukB

2

0

High-throughput

0.576

High

492545

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

2

0

High-throughput

0.576

High

492531

GLUQ
Glutamyl-Q tRNA(Asp) synthetase

2

1

High-throughput

0.571

High

469896

USG
USG-1 protein

2

0

High-throughput

0.563

High

477369

T1RK
Type I restriction enzyme EcoKI endonuclease subunit

2

0

High-throughput

0.563

High

490849

HFQ
RNA-binding protein Hfq

2

0

High-throughput

0.563

High

491717

KTHY
Thymidylate kinase

2

0

High-throughput

0.563

High

492460

RPOZ
DNA-directed RNA polymerase subunit omega

2

0

High-throughput

0.563

High

492461

TGT
Queuine tRNA-ribosyltransferase

2

0

High-throughput

0.563

High

492463

TUSA
Sulfur carrier protein TusA

2

0

High-throughput

0.563

High

492471

ULAR
HTH-type transcriptional regulator UlaR

2

0

High-throughput

0.563

High

492501

NARJ
Nitrate reductase molybdenum cofactor assembly chaperone NarJ

2

0

High-throughput

0.563

High

492504

PARC
DNA topoisomerase 4 subunit A

2

0

High-throughput

0.563

High

492506

SPOT
Bifunctional

2

0

High-throughput

0.563

High

492512

SECA
Protein translocase subunit SecA

2

0

High-throughput

0.563

High

492513

DPO3A
DNA polymerase III subunit alpha

2

0

High-throughput

0.563

High

492521

RNE
Ribonuclease E

2

0

High-throughput

0.563

High

492527

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase PssA

2

0

High-throughput

0.563

High

492539

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.563

High

492544

USPG
Universal stress protein UP12

2

0

High-throughput

0.563

High

492556

NFI
Endonuclease V

2

0

High-throughput

0.563

High

492563

A2MG
Alpha-2-macroglobulin

2

0

High-throughput

0.563

High

492479

RARA
Replication-associated recombination protein A

2

2

High-throughput

0.537

High

492554

MLAF
Intermembrane phospholipid transport system ATP-binding protein MlaF

2

1

High-throughput

0.537

High

492481

KBAY
D-tagatose-1,6-bisphosphate aldolase subunit KbaY

1

1

High-throughput

0.536

High

492465

YQGF
Putative pre-16S rRNA nuclease

1

0

High-throughput

0.513

High

492492

CRP
DNA-binding transcriptional dual regulator CRP

1

0

High-throughput

0.513

High

492543

XYLF
D-xylose-binding periplasmic protein

1

1

High-throughput

0.494

High

395062

DNAA
Chromosomal replication initiator protein DnaA

1

1

High-throughput

0.484

High

395138

UVRD
DNA helicase II

1

1

High-throughput

0.484

High

420140

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

1

High-throughput

0.484

High

450087

RF2
Peptide chain release factor RF2

1

4

High-throughput

0.484

High

490235

CLPP
ATP-dependent Clp protease proteolytic subunit

1

1

High-throughput

0.484

High

490291

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

3

High-throughput

0.484

High

490325

HSLU
ATP-dependent protease ATPase subunit HslU

1

1

High-throughput

0.484

High

490471

HSCB
Co-chaperone protein HscB

1

1

High-throughput

0.484

High

491309

HSCA
Chaperone protein HscA

1

1

High-throughput

0.484

High

491727

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

1

1

High-throughput

0.484

High

491806

MURA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

1

1

High-throughput

0.484

High

492468

CSPG
Cold shock-like protein CspG

1

5

High-throughput

0.484

High

492470

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

1

High-throughput

0.484

High

492478

IOJAP
Ribosomal silencing factor RsfS

1

1

High-throughput

0.484

High

492497

MAP1
Methionine aminopeptidase

1

1

High-throughput

0.484

High

492522

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

1

High-throughput

0.484

High

492526

TRMA
tRNA/tmRNA

1

1

High-throughput

0.484

High

492538

CBPA
Curved DNA-binding protein

1

2

High-throughput

0.484

High

492551

RSMH
Ribosomal RNA small subunit methyltransferase H

1

1

High-throughput

0.484

High

492557

HDA
DnaA regulatory inactivator Hda

1

1

High-throughput

0.484

High

492555

YQJI
Transcriptional regulator YqjI

1

0

High-throughput

0.479

High

492498

YOAB
RutC family protein YoaB

1

1

High-throughput

0.479

High

365860

DPO1
DNA polymerase I

1

0

High-throughput

0.464

High

395101

DPO3E
DNA polymerase III subunit epsilon

1

0

High-throughput

0.464

High

437524

TSAD
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.464

High

460393

SYL
Leucine--tRNA ligase

1

0

High-throughput

0.464

High

480527

GRPE
Protein GrpE

1

0

High-throughput

0.464

High

490367

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.464

High

491466

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

1

0

High-throughput

0.464

High

491523

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

492117

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.464

High

492161

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.464

High

492189

PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

0

High-throughput

0.464

High

492215

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

492459

RPOA
DNA-directed RNA polymerase subunit alpha

1

0

High-throughput

0.464

High

492469

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

492476

YBAK
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK

1

0

High-throughput

0.464

High

492477

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.464

High

492482

FTSA
Cell division protein FtsA

1

0

High-throughput

0.464

High

492484

DNAG
DNA primase

1

0

High-throughput

0.464

High

492485

HOLE
DNA polymerase III subunit theta

1

0

High-throughput

0.464

High

492490

DNAB
Replicative DNA helicase DnaB

1

0

High-throughput

0.464

High

492499

UVRY
Response regulator UvrY

1

0

High-throughput

0.464

High

492500

FUCM
L-fucose mutarotase

1

0

High-throughput

0.464

High

492507

RHO
Transcription termination factor Rho

1

0

High-throughput

0.464

High

492517

DNLJ
DNA ligase

1

0

High-throughput

0.464

High

492519

MURC
UDP-N-acetylmuramate--L-alanine ligase

1

0

High-throughput

0.464

High

492520

SRMB
ATP-dependent RNA helicase SrmB

1

0

High-throughput

0.464

High

492525

ISPA
Farnesyl diphosphate synthase

1

0

High-throughput

0.464

High

492536

GLMM
Phosphoglucosamine mutase

1

0

High-throughput

0.464

High

492537

RAVA
Regulatory ATPase RavA

1

0

High-throughput

0.464

High

492553

ISPH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase

1

0

High-throughput

0.464

High

489281

ACP
Acyl carrier protein

1

0

High-throughput

0.458

High

492486

EXBD
Biopolymer transport protein ExbD

1

0

High-throughput

0.458

High

492508

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.458

High

492511

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.458

High

492529

YJIA
Zinc chaperone YjiA

1

0

High-throughput

0.458

High

492546

SGCE
Protein SgcE

1

0

High-throughput

0.458

High

492472

ZNUC
Zinc import ATP-binding protein ZnuC

1

1

High-throughput

0.442

High

492487

SURA
Chaperone SurA

1

1

High-throughput

0.442

High

492494

NLPD
Murein hydrolase activator NlpD

1

1

High-throughput

0.437

High

492567

YGER
Uncharacterized lipoprotein YgeR

1

1

High-throughput

0.437

High

491576

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.426

High

492462

TIG
Trigger factor

1

0

Small-scale

0.426

High

491390

NIKR
Nickel-responsive regulator

2

0

High-throughput

0.318

High

492464

NRDR
Transcriptional repressor NrdR

2

0

High-throughput

0.313

High

492533

HOLD
DNA polymerase III subunit psi

2

0

High-throughput

0.313

High

492458

RNPA
Ribonuclease P protein component

2

0

High-throughput

0.307

High

492475

FTSH
ATP-dependent zinc metalloprotease FtsH

2

0

High-throughput

0.307

High

492491

MBHM
Hydrogenase-2 large chain

2

0

High-throughput

0.307

High

492495

FABY
Probable acyltransferase FabY

2

0

High-throughput

0.307

High

492505

ATL
DNA base-flipping protein

2

0

High-throughput

0.307

High

492528

TRHO
tRNA uridine(34) hydroxylase

2

0

High-throughput

0.307

High

492534

HOLC
DNA polymerase III subunit chi

2

0

High-throughput

0.307

High

492541

HRPB
ATP-dependent RNA helicase HrpB

2

0

High-throughput

0.307

High

492550

ABPB
Anti-bacteriophage protein B

2

0

High-throughput

0.307

High

492552

LOLA
Outer-membrane lipoprotein carrier protein

2

0

High-throughput

0.307

High

492558

YBJX
Uncharacterized protein YbjX

2

0

High-throughput

0.307

High

492560

BLUF
Blue light- and temperature-regulated antirepressor BluF

2

0

High-throughput

0.307

High

492561

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

2

0

High-throughput

0.307

High

492480

LPOB
Penicillin-binding protein activator LpoB

1

0

High-throughput

0.282

High

492562

YFBM
Protein YfbM

1

0

High-throughput

0.279

Low

492466

YCJF
UPF0283 membrane protein YcjF

1

0

High-throughput

0.261

Low

492493

LAPA
Lipopolysaccharide assembly protein A

1

0

High-throughput

0.261

Low

492549

TORZ
Trimethylamine-N-oxide reductase 2

1

0

High-throughput

0.261

Low

445393

DPO3X
DNA polymerase III subunit tau

1

0

High-throughput

0.253

Low

466607

ILVB
Acetolactate synthase isozyme 1 large subunit

1

0

High-throughput

0.253

Low

492019

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

492489

KDTA
3-deoxy-D-manno-octulosonic acid transferase

1

0

High-throughput

0.253

Low

492515

TOP3
DNA topoisomerase 3

1

0

High-throughput

0.253

Low

492518

MURG
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

1

0

High-throughput

0.253

Low

492524

MURI
Glutamate racemase

1

0

High-throughput

0.253

Low

492532

HOLA
DNA polymerase III subunit delta

1

0

High-throughput

0.253

Low

492542

RPIB
Ribose-5-phosphate isomerase B

1

0

High-throughput

0.253

Low

492566

QUEC
7-cyano-7-deazaguanine synthase

1

0

High-throughput

0.253

Low

492488

FTSX
Cell division protein FtsX

1

0

High-throughput

0.249

Low

492530

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.249

Low

492548

YHHW
Quercetin 2,3-dioxygenase

1

0

High-throughput

0.249

Low

492564

YBCK
Uncharacterized protein YbcK

1

0

High-throughput

0.249

Low

492568

UACT
Uric acid transporter UacT

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025