Protein: CDC45
Cell division control protein 45

Gene: CDC45
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: Q08032

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

675563

MCM4
DNA replication licensing factor MCM4

26

16

Small-scale

0.990

High

667640

MCM2
DNA replication licensing factor MCM2

22

15

Small-scale

0.990

High

976275

SLD5
DNA replication complex GINS protein SLD5

22

3

Small-scale

0.989

High

622198

MCM3
DNA replication licensing factor MCM3

19

15

Small-scale

0.985

High

667899

MCM5
Minichromosome maintenance protein 5

17

17

Small-scale

0.983

High

859026

MCM6
DNA replication licensing factor MCM6

15

18

Small-scale

0.981

High

744795

MCM7
DNA replication licensing factor MCM7

14

15

Small-scale

0.980

High

772612

PSF2
DNA replication complex GINS protein PSF2

8

3

Small-scale

0.959

High

964875

CTF4
DNA polymerase alpha-binding protein

8

1

Small-scale

0.957

High

993244

PSF1
DNA replication complex GINS protein PSF1

6

3

Small-scale

0.936

High

993243

PSF3
DNA replication complex GINS protein PSF3

4

2

Small-scale

0.885

High

993239

CDC45
Cell division control protein 45

2

0

Small-scale

0.758

High

688673

MCM10
Minichromosome maintenance protein 10

8

2

Small-scale

0.750

High

859482

SLD3
DNA replication regulator SLD3

12

0

Small-scale

0.729

High

622900

DPB2
DNA polymerase epsilon subunit B

6

1

Small-scale

0.719

High

526867

DPOLA
DNA polymerase alpha catalytic subunit A

5

4

Small-scale

0.714

High

865234

TOF1
Topoisomerase 1-associated factor 1

4

1

Small-scale

0.683

High

634905

MRC1
Mediator of replication checkpoint protein 1

5

0

Small-scale

0.676

High

606155

RAD53
Serine/threonine-protein kinase RAD53

2

1

Small-scale

0.642

High

602382

DPOE
DNA polymerase epsilon catalytic subunit A

3

4

Small-scale

0.641

High

980143

CSM3
Chromosome segregation in meiosis protein 3

3

0

Small-scale

0.619

High

810655

DPB11
DNA replication regulator DPB11

2

1

Small-scale

0.602

High

607350

RFA1
Replication factor A protein 1

2

1

Small-scale

0.584

High

609149

SIN3
Transcriptional regulatory protein SIN3

2

0

High-throughput

0.576

High

693068

RPD3
Histone deacetylase RPD3

2

0

High-throughput

0.576

High

993241

DIA2
Protein DIA2

2

0

Small-scale

0.547

High

972922

IMA1
Importin subunit alpha

1

2

Small-scale

0.501

High

691131

HOG1
Mitogen-activated protein kinase HOG1

1

2

Small-scale

0.479

High

858708

UFD1
Ubiquitin fusion degradation protein 1

1

1

Small-scale

0.479

High

375525

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

515091

MCM1
Pheromone receptor transcription factor

1

0

Small-scale

0.458

High

588243

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.458

High

663492

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

751454

NSE2
E3 SUMO-protein ligase MMS21

1

0

Small-scale

0.458

High

836968

CTF18
Chromosome transmission fidelity protein 18

1

0

Small-scale

0.458

High

960023

SEN1
Helicase SEN1

1

0

Small-scale

0.458

High

978327

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

986261

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

993240

SLD7
Mitochondrial morphogenesis protein SLD7

1

0

Small-scale

0.458

High

512961

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

633631

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

769634

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

993242

CDC53
Cell division control protein 53

1

1

High-throughput

0.445

High

356760

H4
Histone H4

1

0

High-throughput

0.426

High

376950

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

495117

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

646645

DPB3
DNA polymerase epsilon subunit C

1

0

Small-scale

0.426

High

692946

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.426

High

853185

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.426

High

979817

DPB4
DNA polymerase epsilon subunit D

1

0

Small-scale

0.426

High

993245

H2AZ
Histone H2A.Z

1

0

High-throughput

0.426

High

774675

LYS12
Homoisocitrate dehydrogenase, mitochondrial

2

0

High-throughput

0.313

High

969463

TOF2
Topoisomerase 1-associated factor 2

1

0

Small-scale

0.249

Low

361052

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

368451

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

424745

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

556336

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

785244

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024