Protein: SENP8
Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)

Gene: SENP8
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q96LD8

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0008234 - cysteine-type peptidase activity
GO:0019784 - deNEDDylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1079578

NEDD8
NEDD8

6

6

Small-scale

0.948

High

1041149

CUL1
Cullin-1

2

7

Small-scale

0.629

High

856151

CHIO
Beta-chimaerin

2

1

High-throughput

0.606

High

897295

CSN2
COP9 signalosome complex subunit 2

1

1

Small-scale

0.561

High

803959

NSF
Vesicle-fusing ATPase

1

2

High-throughput

0.515

High

1043166

CUL4A
Cullin-4A

1

8

Small-scale

0.512

High

714363

HSP74
Heat shock 70 kDa protein 4

1

4

Small-scale

0.501

High

923159

RL11
Large ribosomal subunit protein uL5

1

1

Small-scale

0.501

High

1024207

CSN1
COP9 signalosome complex subunit 1

1

1

Small-scale

0.501

High

1041437

CUL2
Cullin-2

1

7

Small-scale

0.501

High

1297116

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

5

High-throughput

0.501

High

1297117

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

3

Small-scale

0.501

High

1297119

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

3

High-throughput

0.501

High

1297121

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

High-throughput

0.501

High

1297120

HDGR3
Hepatoma-derived growth factor-related protein 3

1

0

High-throughput

0.493

High

896185

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

Small-scale

0.480

High

910530

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

537571

PA2GA
Phospholipase A2, membrane associated

1

1

Small-scale

0.457

High

1291460

IFT43
Intraflagellar transport protein 43 homolog

2

0

High-throughput

0.328

High

1297118

AKIP1
A-kinase-interacting protein 1

1

0

Small-scale

0.292

High

869715

TERF1
Telomeric repeat-binding factor 1

1

0

Small-scale

0.261

Low

517410

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024