Protein: ISY1
Pre-mRNA-splicing factor ISY1 (Interactor of SYF1) (PRP19-associated complex protein 30)

Gene: ISY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P21374

Gene Ontology (top 5):
GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000389 - mRNA 3'-splice site recognition
GO:0000974 - Prp19 complex
GO:0005737 - cytoplasm
GO:0071006 - U2-type catalytic step 1 spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598656

CWC2
Pre-mRNA-splicing factor CWC2

3

2

High-throughput

0.847

High

598647

SYF1
Pre-mRNA-splicing factor SYF1

10

6

Small-scale

0.761

High

598616

PRP19
Pre-mRNA-processing factor 19

12

3

Small-scale

0.758

High

598613

YJU2
Splicing factor YJU2

2

2

Small-scale

0.754

High

598657

CLF1
Pre-mRNA-splicing factor CLF1

6

6

Small-scale

0.740

High

598645

CEF1
Pre-mRNA-splicing factor CEF1

4

2

Small-scale

0.698

High

598655

RU2A
U2 small nuclear ribonucleoprotein A'

4

2

Small-scale

0.683

High

598624

NTC20
Pre-mRNA-splicing factor NTC20

3

0

Small-scale

0.622

High

598619

PRP8
Pre-mRNA-splicing factor 8

1

3

High-throughput

0.618

High

598658

PRP46
Pre-mRNA-splicing factor PRP46

2

2

High-throughput

0.611

High

598609

ISY1
Pre-mRNA-splicing factor ISY1

2

1

Small-scale

0.609

High

598635

SYF2
Pre-mRNA-splicing factor SYF2

2

0

Small-scale

0.595

High

598622

NTR2
Pre-mRNA-splicing factor NTR2

2

0

Small-scale

0.585

High

598649

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.585

High

554200

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

2

4

Small-scale

0.584

High

589411

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

4

High-throughput

0.584

High

598626

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

2

High-throughput

0.584

High

598651

SP382
Pre-mRNA-splicing factor SPP382

2

0

Small-scale

0.576

High

598644

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

598618

BRR2
Pre-mRNA-splicing helicase BRR2

2

5

High-throughput

0.558

High

598654

NCBP2
Nuclear cap-binding protein subunit 2

2

2

High-throughput

0.533

High

598615

XPO1
Exportin-1

1

0

High-throughput

0.513

High

598610

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

4

High-throughput

0.479

High

598612

PRP45
Pre-mRNA-processing protein 45

1

2

High-throughput

0.479

High

598617

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.479

High

598621

SN114
Pre-mRNA-splicing factor SNU114

1

3

High-throughput

0.479

High

598623

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.479

High

598628

RUXG
Small nuclear ribonucleoprotein G

1

3

High-throughput

0.479

High

598630

PRP17
Pre-mRNA-processing factor 17

1

4

High-throughput

0.479

High

598631

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.479

High

598638

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.479

High

598632

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

598634

SF3B1
U2 snRNP component HSH155

1

0

High-throughput

0.458

High

598636

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

598639

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

598640

SPP2
Pre-mRNA-splicing factor SPP2

1

0

High-throughput

0.458

High

598641

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.458

High

598642

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

598646

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

598650

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

598652

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

598653

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.458

High

598625

PRP39
Pre-mRNA-processing factor 39

1

6

Small-scale

0.439

High

598611

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.437

High

598629

MSL1
U2 small nuclear ribonucleoprotein B''

1

3

High-throughput

0.437

High

598648

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.437

High

598627

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

598633

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

598637

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.298

High

586458

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.249

Low

598614

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

598620

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.249

Low

598643

XRN2
5'-3' exoribonuclease 2

1

0

Small-scale

0.249

Low

598659

HSH49
Protein HSH49

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024