Protein: ESM8
Enhancer of split m8 protein (E(spl)m8)

Gene: ESM8, E(spl)m8-HLH
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: P13098

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0007498 - mesoderm development
GO:0010629 - negative regulation of gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

542895

DA
Protein daughterless

2

8

Small-scale

0.768

High

560199

ESM8
Enhancer of split m8 protein

2

16

Small-scale

0.768

High

560209

ESMC
Enhancer of split mgamma protein

2

16

Small-scale

0.768

High

560201

GROU
Protein groucho

9

20

Small-scale

0.750

High

560200

HAIR
Protein hairy

1

16

Small-scale

0.724

High

560161

ESM5
Enhancer of split m5 protein

2

16

Small-scale

0.723

High

560175

ESM7
Enhancer of split m7 protein

2

17

Small-scale

0.723

High

467096

CSK2A
Casein kinase II subunit alpha

3

11

Small-scale

0.672

High

560208

ESMB
Enhancer of split mbeta protein

1

16

Small-scale

0.656

High

560210

ESMD
Enhancer of split mdelta protein

1

16

Small-scale

0.656

High

560204

ATO
Protein atonal

1

20

Small-scale

0.621

High

560221

Q9VDE3
LD08669p

2

9

High-throughput

0.571

High

234444

CTBP
C-terminal-binding protein

1

3

High-throughput

0.541

High

560202

ESCA
Protein escargot

1

2

High-throughput

0.541

High

560212

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

560219

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

5

High-throughput

0.541

High

560220

Q9V9V8
LP07209p

1

1

High-throughput

0.541

High

560207

TBB2
Tubulin beta-2 chain

2

5

High-throughput

0.521

High

560213

RS15B
Small ribosomal subunit protein uS8B

2

1

High-throughput

0.521

High

560214

Q86BK8
Ras-related protein Rab-14

2

2

High-throughput

0.521

High

560206

COLL
Transcription factor collier

1

0

High-throughput

0.518

High

518451

AST5
Achaete-scute complex protein T5

1

20

High-throughput

0.492

High

518483

AST4
Achaete-scute complex protein T4

1

20

High-throughput

0.492

High

560215

Q8I0J6
Degringolade, isoform B

1

10

Small-scale

0.479

High

560223

DGT2
Augmin complex subunit dgt2

1

1

High-throughput

0.464

High

305454

O77430
GEO01111p1

1

3

High-throughput

0.445

High

538200

HSP7B
Heat shock 70 kDa protein cognate 2

1

8

High-throughput

0.445

High

560203

HSP7A
Heat shock 70 kDa protein cognate 1

1

6

High-throughput

0.445

High

118682

M9NF85
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

304107

RAB7
Ras-related protein Rab7

1

1

High-throughput

0.437

High

560217

Q8IQG0
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

560216

Q8IQ04
GEO11681p1

1

0

High-throughput

0.282

High

560222

GYS
Glycogen [starch] synthase

1

0

High-throughput

0.265

Low

560211

Q0E8Q7
Engulfment ABC transporter in the ovary, isoform B

1

0

High-throughput

0.251

Low

560205

FBP2
Fat body protein 2

1

0

High-throughput

0.249

Low

560218

Q8MSL7
AT25132p

1

0

High-throughput

0.249

Low

560224

WASC3
WASH complex subunit 3

1

0

High-throughput

0.249

Low

560225

Q9VQI7
1-Cys peroxiredoxin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025