HitPredict
Protein: M3K8
Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2)

Gene: M3K8, Map3k8
Organism: Mus musculus
Interactions: 4
UniProt ID: Q07174

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002376 - immune system process
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

681978

 NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

15

Small-scale

 0.754

High

1058977

 RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

17

Small-scale

 0.665

High

1058979

 TNIP2
TNFAIP3-interacting protein 2

1

1

Small-scale

 0.536

High

1058978

 KCD20
BTB/POZ domain-containing protein KCTD20

1

5

High-throughput

 0.417

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025