Protein: SCN1A
Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1)

Gene: SCN1A
Organism: Homo sapiens
Interactions: 14
UniProt ID: P35498

Gene Ontology (top 5):
GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0006814 - sodium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

771748

SCN1B
Sodium channel regulatory subunit beta-1

1

3

Small-scale

0.618

High

771752

SCN4B
Sodium channel regulatory subunit beta-4

1

4

Small-scale

0.618

High

771749

SNTA1
Alpha-1-syntrophin

1

12

Small-scale

0.527

High

771743

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

20

High-throughput

0.501

High

771744

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.501

High

771747

FGF12
Fibroblast growth factor 12

1

7

Small-scale

0.501

High

771756

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

20

High-throughput

0.501

High

771746

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

771751

LARP7
La-related protein 7

1

8

High-throughput

0.479

High

771755

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

771745

PSN1
Presenilin-1

1

0

High-throughput

0.460

High

771750

NEDD8
Ubiquitin-like protein NEDD8

1

1

Small-scale

0.445

High

771753

ESR2
Estrogen receptor beta

1

3

High-throughput

0.445

High

771754

GAN
Gigaxonin

1

5

High-throughput

0.437

High


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Last updated: 11Aug2025