HitPredict - High confidence protein-protein interactions

Protein: HEPC
Hepcidin (Liver-expressed antimicrobial peptide 1) (LEAP-1) (Putative liver tumor regressor) (PLTR) [Cleaved into: Hepcidin-25 (Hepc25); Hepcidin-20 (Hepc20)]

Gene: HEPC, HAMP
Organism: Homo sapiens
Interactions: 5
UniProt ID: P81172

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006879 - intracellular iron ion homeostasis

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
851514	GATA4 Transcription factor GATA-4	2	1	Small-scale	0.601	High
1010437	GATA6 Transcription factor GATA-6	1	1	Small-scale	0.515	High
846060	GLP1R Glucagon-like peptide 1 receptor	1	0	Small-scale	0.251	Low
1010436	CKAP4 Cytoskeleton-associated protein 4	1	0	High-throughput	0.251	Low
1010438	VKOR1 Vitamin K epoxide reductase complex subunit 1	1	0	Small-scale	0.251	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025