HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	23245942
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 400
+	Hs
		862030 TCPB_HUMAN (1-535): 0: 586: 100.00		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		861918 TCPG_HUMAN (3-532): 0: 561: 28.33		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		610567 TCPA_HUMAN (5-533): 0: 541: 34.30		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		861914 TCPE_HUMAN (1-528): 0: 541: 32.29		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		131941 TCPB_HUMAN (1-535): 0: 586: 100.00		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		1407583 TCPH_HUMAN (4-532): 0: 591: 34.08		SMUF1_HUMAN (55-362): 3.98e-51: 184: 16.62
+	Hs
		882091 TCPG_HUMAN (3-532): 0: 561: 28.33		ITCH_HUMAN (37-356): 2.66e-60: 211: 14.83
+	Hs
		1007293 TCPB_HUMAN (1-535): 0: 586: 100.00		SMUF1_HUMAN (55-362): 3.98e-51: 184: 16.62
+	Hs
		131823 TCPG_HUMAN (3-532): 0: 561: 28.33		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		131820 TCPE_HUMAN (1-528): 0: 541: 32.29		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		610902 TCPA_HUMAN (5-533): 0: 541: 34.30		SMUF1_HUMAN (55-362): 3.98e-51: 184: 16.62
+	Hs
		1407601 TCPH_HUMAN (4-532): 0: 591: 34.08		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1007315 TCPB_HUMAN (1-535): 0: 586: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09