HitPredict

Interactor 1: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Interactor 2: ETS2 (P15037)
Protein C-ets-2
Gene: ETS2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	15572696, 14722092
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2441 Mm			1 468
+	Mm
		542771 CBP_MOUSE (1-2441): 0: 1114: 99.55		ETS2_MOUSE (1-468): 0: 599: 100.00
+	Hs
		542756 CBP_HUMAN (1-2441): 0: 1094: 94.89		ETS2_HUMAN (1-468): 0: 600: 90.83
+	Mm
		101425 F8VPR5_MOUSE (1-2441): 0: 1127: 100.00		ETS1_MOUSE (60-467): 2.59e-145: 424: 54.63
+	Mm
		649230 CBP_MOUSE (1-2441): 0: 1114: 99.55		ETS1_MOUSE (60-467): 2.59e-145: 424: 54.63
+	Hs
		542053 CBP_HUMAN (1-2441): 0: 1094: 94.89		ETS1_HUMAN (60-468): 6.92e-147: 428: 54.50
+	Hs
		542741 EP300_HUMAN (1-2426): 0: 887: 54.94		ETS2_HUMAN (1-468): 0: 600: 90.83
+	Hs
		507480 CBP_HUMAN (1-2441): 0: 1094: 94.89		ERG_HUMAN (40-441): 6.24e-93: 291: 27.54
+	Hs
		542006 EP300_HUMAN (1-2426): 0: 887: 54.94		ETS1_HUMAN (60-468): 6.92e-147: 428: 54.50
+	Mm
		101420 F8VPR5_MOUSE (1-2441): 0: 1127: 100.00		SPI1_MOUSE (259-456): 1.14e-38: 143: 22.58
+	Mm
		101434 F8VPR5_MOUSE (1-2441): 0: 1127: 100.00		GABPA_MOUSE (42-196): 7.64e-35: 137: 29.30
+	Hs
		794560 CBP_HUMAN (1-2441): 0: 1094: 94.89		ETV4_HUMAN (170-452): 5.25e-45: 165: 24.15
+	Hs
		1270772 CBP_HUMAN (1-2441): 0: 1094: 94.89		FEV_HUMAN (344-441): 1.61e-46: 162: 63.27
+	Hs
		584268 CBP_HUMAN (1-2441): 0: 1094: 94.89		ELK1_HUMAN (361-446): 4.37e-38: 145: 60.92
+	Hs
		507409 EP300_HUMAN (1-2426): 0: 887: 54.94		ERG_HUMAN (40-441): 6.24e-93: 291: 27.54
+	Hs
		840433 EP300_HUMAN (1-2426): 0: 887: 54.94		ETV1_HUMAN (163-452): 2.14e-67: 225: 26.77
+	Hs
		781139 EP300_HUMAN (1-2426): 0: 887: 54.94		ETV5_HUMAN (179-452): 7.3e-59: 203: 26.92
+	Hs
		794535 EP300_HUMAN (1-2426): 0: 887: 54.94		ETV4_HUMAN (170-452): 5.25e-45: 165: 24.15
+	Mm
		70899 EP300_MOUSE (1-2426): 0: 889: 53.65		ETV4_MOUSE (199-452): 1.02e-43: 162: 27.07
+	Hs
		584244 EP300_HUMAN (1-2426): 0: 887: 54.94		ELK1_HUMAN (361-446): 4.37e-38: 145: 60.92
+	Mm
		70891 EP300_MOUSE (1-2426): 0: 889: 53.65		SPI1_MOUSE (259-456): 1.14e-38: 143: 22.58