Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
RPB1
DNA-directed RNA polymerase II subunit RPB1 |
8 |
10 |
Small-scale |
0.964 | High |
|
|
RPA1
DNA-directed RNA polymerase I subunit RPA1 |
6 |
10 |
Small-scale |
0.943 | High |
|
|
RPB3
DNA-directed RNA polymerase II subunit RPB3 |
4 |
4 |
Small-scale |
0.899 | High |
|
|
RPB11
DNA-directed RNA polymerase II subunit RPB11-a |
4 |
3 |
High-throughput |
0.895 | High |
|
|
RPC1
DNA-directed RNA polymerase III subunit RPC1 |
4 |
10 |
Small-scale |
0.886 | High |
|
|
RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1 |
3 |
4 |
High-throughput |
0.861 | High |
|
|
RPB7
DNA-directed RNA polymerase II subunit RPB7 |
7 |
5 |
Small-scale |
0.746 | High |
|
|
RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5 |
5 |
1 |
Small-scale |
0.714 | High |
|
|
RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2 |
4 |
3 |
High-throughput |
0.694 | High |
|
|
RPC8
DNA-directed RNA polymerase III subunit RPC8 |
4 |
5 |
High-throughput |
0.694 | High |
|
|
RPB2
DNA-directed RNA polymerase II subunit RPB2 |
4 |
6 |
Small-scale |
0.689 | High |
|
|
RPB4
DNA-directed RNA polymerase II subunit RPB4 |
3 |
1 |
Small-scale |
0.670 | High |
|
|
RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1 |
3 |
1 |
Small-scale |
0.670 | High |
|
|
RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 |
3 |
1 |
High-throughput |
0.667 | High |
|
|
RPC10
DNA-directed RNA polymerase III subunit RPC10 |
3 |
5 |
High-throughput |
0.667 | High |
|
|
RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4 |
3 |
1 |
Small-scale |
0.660 | High |
|
|
RMP
Unconventional prefoldin RPB5 interactor 1 |
3 |
1 |
Small-scale |
0.656 | High |
|
|
RPC4
DNA-directed RNA polymerase III subunit RPC4 |
3 |
2 |
Small-scale |
0.656 | High |
|
|
RPC5
DNA-directed RNA polymerase III subunit RPC5 |
3 |
2 |
High-throughput |
0.656 | High |
|
|
RPC2
DNA-directed RNA polymerase III subunit RPC2 |
3 |
6 |
Small-scale |
0.650 | High |
|
|
MED19
Mediator of RNA polymerase II transcription subunit 19 |
3 |
0 |
High-throughput |
0.638 | High |
|
|
MED26
Mediator of RNA polymerase II transcription subunit 26 |
3 |
0 |
High-throughput |
0.638 | High |
|
|
PIHD1
PIH1 domain-containing protein 1 |
3 |
0 |
High-throughput |
0.628 | High |
|
|
RPC9
DNA-directed RNA polymerase III subunit RPC9 |
2 |
1 |
High-throughput |
0.611 | High |
|
|
RPB9
DNA-directed RNA polymerase II subunit RPB9 |
2 |
5 |
High-throughput |
0.611 | High |
|
|
TF2B
Transcription initiation factor IIB |
2 |
3 |
High-throughput |
0.611 | High |
|
|
RPA49
DNA-directed RNA polymerase I subunit RPA49 |
2 |
1 |
High-throughput |
0.611 | High |
|
|
RPA2
DNA-directed RNA polymerase I subunit RPA2 |
2 |
6 |
High-throughput |
0.611 | High |
|
|
RPA12
DNA-directed RNA polymerase I subunit RPA12 |
2 |
5 |
High-throughput |
0.611 | High |
|
|
RUVB2
RuvB-like 2 |
2 |
2 |
High-throughput |
0.611 | High |
|
|
BARD1
BRCA1-associated RING domain protein 1 |
2 |
0 |
Small-scale |
0.603 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
2 |
1 |
Small-scale |
0.602 | High |
|
|
RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B |
2 |
4 |
High-throughput |
0.601 | High |
|
|
DAA10
Dynein axonemal assembly factor 10 |
3 |
1 |
High-throughput |
0.599 | High |
|
|
ERCC6
DNA excision repair protein ERCC-6 |
2 |
1 |
Small-scale |
0.595 | High |
|
|
RPA34
DNA-directed RNA polymerase I subunit RPA34 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
INT3
Integrator complex subunit 3 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
MED10
Mediator of RNA polymerase II transcription subunit 10 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
RPAP3
RNA polymerase II-associated protein 3 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
UXT
Protein UXT |
2 |
0 |
High-throughput |
0.585 | High |
|
|
PFD2
Prefoldin subunit 2 |
2 |
0 |
High-throughput |
0.585 | High |
|
|
BRD4
Bromodomain-containing protein 4 |
2 |
1 |
Small-scale |
0.584 | High |
|
|
MYC
Myc proto-oncogene protein |
2 |
1 |
High-throughput |
0.584 | High |
|
|
RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2 |
1 |
3 |
High-throughput |
0.575 | High |
|
|
ESR1
Estrogen receptor |
2 |
2 |
High-throughput |
0.571 | High |
|
|
MED9
Mediator of RNA polymerase II transcription subunit 9 |
2 |
0 |
High-throughput |
0.559 | High |
|
|
RPC7
DNA-directed RNA polymerase III subunit RPC7 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
CSK22
Casein kinase II subunit alpha' |
1 |
1 |
High-throughput |
0.536 | High |
|
|
CSK21
Casein kinase II subunit alpha |
1 |
1 |
High-throughput |
0.536 | High |
|
|
KGP1
cGMP-dependent protein kinase 1 |
1 |
2 |
High-throughput |
0.536 | High |
|
|
SPT6H
Transcription elongation factor SPT6 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
TF3B
Transcription factor IIIB 90 kDa subunit |
1 |
3 |
High-throughput |
0.536 | High |
|
|
RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A |
1 |
4 |
High-throughput |
0.536 | High |
|
|
RPC7L
DNA-directed RNA polymerase III subunit RPC7-like |
1 |
1 |
High-throughput |
0.536 | High |
|
|
RPC3
DNA-directed RNA polymerase III subunit RPC3 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
RPC6
DNA-directed RNA polymerase III subunit RPC6 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
RUVB1
RuvB-like 1 |
1 |
2 |
High-throughput |
0.536 | High |
|
|
CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase |
1 |
1 |
High-throughput |
0.536 | High |
|
|
GRL1A
DNA-directed RNA polymerase II subunit GRINL1A |
2 |
0 |
High-throughput |
0.528 | High |
|
|
UBE2W
Ubiquitin-conjugating enzyme E2 W |
1 |
0 |
Small-scale |
0.527 | High |
|
|
SOCS2
Suppressor of cytokine signaling 2 |
1 |
1 |
High-throughput |
0.515 | High |
|
|
SOCS6
Suppressor of cytokine signaling 6 |
1 |
1 |
High-throughput |
0.515 | High |
|
|
BDP1
Transcription factor TFIIIB component B'' homolog |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MED7
Mediator of RNA polymerase II transcription subunit 7 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
DLDH
Dihydrolipoyl dehydrogenase, mitochondrial |
1 |
0 |
High-throughput |
0.513 | High |
|
|
RBTN2
Rhombotin-2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
HD
Huntingtin |
1 |
0 |
High-throughput |
0.513 | High |
|
|
SPB8
Serpin B8 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
IMA1
Importin subunit alpha-1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MK06
Mitogen-activated protein kinase 6 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
TRM1L
tRNA |
1 |
0 |
High-throughput |
0.513 | High |
|
|
RYBP
RING1 and YY1-binding protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
STK35
Serine/threonine-protein kinase 35 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
NELFB
Negative elongation factor B |
1 |
0 |
High-throughput |
0.513 | High |
|
|
JARD2
Protein Jumonji |
1 |
0 |
High-throughput |
0.513 | High |
|
|
EPAS1
Endothelial PAS domain-containing protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MED18
Mediator of RNA polymerase II transcription subunit 18 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MAF1
Repressor of RNA polymerase III transcription MAF1 homolog |
1 |
0 |
High-throughput |
0.513 | High |
|
|
NELFA
Negative elongation factor A |
1 |
0 |
High-throughput |
0.513 | High |
|
|
INT9
Integrator complex subunit 9 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MED29
Mediator of RNA polymerase II transcription subunit 29 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
MED31
Mediator of RNA polymerase II transcription subunit 31 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
NDKB
Nucleoside diphosphate kinase B |
1 |
0 |
High-throughput |
0.493 | High |
|
|
GPN3
GPN-loop GTPase 3 |
1 |
3 |
High-throughput |
0.489 | High |
|
|
RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3 |
1 |
0 |
Small-scale |
0.480 | High |
|
|
PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
1 |
0 |
High-throughput |
0.480 | High |
|
|
SPT5H
Transcription elongation factor SPT5 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
SPOP
Speckle-type POZ protein |
1 |
1 |
High-throughput |
0.479 | High |
|
|
MED14
Mediator of RNA polymerase II transcription subunit 14 |
1 |
4 |
High-throughput |
0.479 | High |
|
|
MCE1
mRNA-capping enzyme |
1 |
2 |
High-throughput |
0.479 | High |
|
|
MED6
Mediator of RNA polymerase II transcription subunit 6 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
RECQ4
ATP-dependent DNA helicase Q4 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
RECQ5
ATP-dependent DNA helicase Q5 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
MYCN
N-myc proto-oncogene protein |
1 |
1 |
High-throughput |
0.479 | High |
|
|
ANDR
Androgen receptor |
1 |
2 |
High-throughput |
0.479 | High |
|
|
T2FB
General transcription factor IIF subunit 2 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
PHB1
Prohibitin 1 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
SYUA
Alpha-synuclein |
1 |
1 |
High-throughput |
0.479 | High |
|
|
CDK8
Cyclin-dependent kinase 8 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
WDR5
WD repeat-containing protein 5 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
H4
Histone H4 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
FOXO1
Forkhead box protein O1 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
BRD3
Bromodomain-containing protein 3 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
MD13L
Mediator of RNA polymerase II transcription subunit 13-like |
1 |
1 |
High-throughput |
0.479 | High |
|
|
HUWE1
E3 ubiquitin-protein ligase HUWE1 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
ESR2
Estrogen receptor beta |
1 |
2 |
High-throughput |
0.479 | High |
|
|
MED12
Mediator of RNA polymerase II transcription subunit 12 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
FBXW7
F-box/WD repeat-containing protein 7 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
RING2
E3 ubiquitin-protein ligase RING2 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
CDK19
Cyclin-dependent kinase 19 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
SFR19
Splicing factor, arginine/serine-rich 19 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
GPN1
GPN-loop GTPase 1 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
DNM3B
DNA |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MED13
Mediator of RNA polymerase II transcription subunit 13 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
XPO7
Exportin-7 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
DNM3A
DNA |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MEN1
Menin |
1 |
0 |
High-throughput |
0.458 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
1 |
0 |
High-throughput |
0.458 | High |
|
|
NUPR1
Nuclear protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SCAF4
SR-related and CTD-associated factor 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MET18
Histidine protein methyltransferase 1 homolog |
1 |
0 |
High-throughput |
0.458 | High |
|
|
BAG3
BAG family molecular chaperone regulator 3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TCTP
Translationally-controlled tumor protein |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CEBPB
CCAAT/enhancer-binding protein beta |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CCNC
Cyclin-C |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CCNF
Cyclin-F |
1 |
0 |
High-throughput |
0.458 | High |
|
|
GATA4
Transcription factor GATA-4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MP2K4
Dual specificity mitogen-activated protein kinase kinase 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
NR2C2
Nuclear receptor subfamily 2 group C member 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MECP2
Methyl-CpG-binding protein 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
FOXA1
Hepatocyte nuclear factor 3-alpha |
1 |
0 |
High-throughput |
0.458 | High |
|
|
NLRP6
NACHT, LRR and PYD domains-containing protein 6 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
ELOF1
Transcription elongation factor 1 homolog |
1 |
0 |
Small-scale |
0.458 | High |
|
|
UBE2H
Ubiquitin-conjugating enzyme E2 H |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED21
Mediator of RNA polymerase II transcription subunit 21 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CUL3
Cullin-3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TNIP1
TNFAIP3-interacting protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
U5S1
116 kDa U5 small nuclear ribonucleoprotein component |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED22
Mediator of RNA polymerase II transcription subunit 22 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED1
Mediator of RNA polymerase II transcription subunit 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
IKBB
NF-kappa-B inhibitor beta |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CL16A
Protein CLEC16A |
1 |
0 |
High-throughput |
0.458 | High |
|
|
IFIX
Pyrin and HIN domain-containing protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED27
Mediator of RNA polymerase II transcription subunit 27 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
PRP8
Pre-mRNA-processing-splicing factor 8 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
INT5
Integrator complex subunit 5 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
UBP37
Ubiquitin carboxyl-terminal hydrolase 37 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
CEP57
Centrosomal protein of 57 kDa |
1 |
0 |
High-throughput |
0.458 | High |
|
|
INT1
Integrator complex subunit 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TNIP2
TNFAIP3-interacting protein 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED8
Mediator of RNA polymerase II transcription subunit 8 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED30
Mediator of RNA polymerase II transcription subunit 30 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
CI072
Guanine nucleotide exchange factor C9orf72 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TBX5
T-box transcription factor TBX5 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
FACD2
Fanconi anemia group D2 protein |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED28
Mediator of RNA polymerase II transcription subunit 28 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
EGLN3
Prolyl hydroxylase EGLN3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED20
Mediator of RNA polymerase II transcription subunit 20 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED4
Mediator of RNA polymerase II transcription subunit 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED17
Mediator of RNA polymerase II transcription subunit 17 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
INT10
Integrator complex subunit 10 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
MED11
Mediator of RNA polymerase II transcription subunit 11 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
INT6
Integrator complex subunit 6 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein |
1 |
1 |
High-throughput |
0.437 | High |
|
|
RASF8
Ras association domain-containing protein 8 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
PHRF1
PHD and RING finger domain-containing protein 1 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
RPC22
Protein POLR1D, isoform 2 |
1 |
0 |
High-throughput |
0.426 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
0 |
High-throughput |
0.426 | High |
|
|
BAP18
BPTF-associated chromatin complex component 1 |
1 |
0 |
High-throughput |
0.426 | High |
|
|
LN28A
Protein lin-28 homolog A |
1 |
0 |
High-throughput |
0.426 | High |
|
|
PDRG1
p53 and DNA damage-regulated protein 1 |
2 |
0 |
High-throughput |
0.318 | High |
|
|
GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 |
2 |
0 |
High-throughput |
0.305 | High |
|
|
PFD6
Prefoldin subunit 6 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
HCD2
3-hydroxyacyl-CoA dehydrogenase type-2 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
UVRAG
UV radiation resistance-associated gene protein |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
TNR5
Tumor necrosis factor receptor superfamily member 5 |
1 |
0 |
High-throughput |
0.269 | Low |
|
|
ARSF
Arylsulfatase F |
1 |
0 |
High-throughput |
0.269 | Low |
|
|
EIF1B
Eukaryotic translation initiation factor 1b |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
CD123
Translation initiation factor eIF2 assembly protein |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
M4K2
Mitogen-activated protein kinase kinase kinase kinase 2 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
OTUD1
OTU domain-containing protein 1 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
ZCH18
Zinc finger CCCH domain-containing protein 18 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
PDZD8
PDZ domain-containing protein 8 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
DDRGK
DDRGK domain-containing protein 1 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
PKHA4
Pleckstrin homology domain-containing family A member 4 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
ASND1
Asparagine synthetase domain-containing protein 1 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
ASURF
ASNSD1 upstream open reading frame protein |
1 |
0 |
High-throughput |
0.232 | Low |
|
|
TAGL
Transgelin |
1 |
0 |
High-throughput |
0.232 | Low |
|
|
NEUL4
Neuralized-like protein 4 |
1 |
0 |
High-throughput |
0.232 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
