Protein: RON
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]

Gene: RON, MST1R
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q04912

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0001889 - liver development
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005008 - hepatocyte growth factor receptor activity
GO:0005011 - macrophage colony-stimulating factor receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645876

HGFL
Hepatocyte growth factor-like protein

3

20

Small-scale

0.771

High

924497

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.768

High

646822

1433T
14-3-3 protein theta

2

20

Small-scale

0.743

High

981867

GAB1
GRB2-associated-binding protein 1

1

20

Small-scale

0.713

High

158925

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.691

High

861709

PLK1
Serine/threonine-protein kinase PLK1

1

13

High-throughput

0.691

High

926953

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.691

High

981930

BTNL2
Butyrophilin-like protein 2

1

20

High-throughput

0.691

High

165192

PLXB2
Plexin-B2

1

20

Small-scale

0.665

High

195978

PLXB1
Plexin-B1

1

19

Small-scale

0.665

High

981931

PLXB3
Plexin-B3

1

20

Small-scale

0.665

High

681800

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

Small-scale

0.647

High

610364

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.646

High

383759

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

981878

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

20

High-throughput

0.621

High

580981

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

20

Small-scale

0.618

High

581160

EPOR
Erythropoietin receptor

1

20

Small-scale

0.618

High

666078

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.618

High

683284

1433B
14-3-3 protein beta/alpha

1

20

Small-scale

0.618

High

683980

1433S
14-3-3 protein sigma

1

20

Small-scale

0.618

High

805397

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

20

High-throughput

0.618

High

809276

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

20

High-throughput

0.618

High

854173

JAK3
Tyrosine-protein kinase JAK3

1

20

High-throughput

0.618

High

904469

1433G
14-3-3 protein gamma

1

20

Small-scale

0.618

High

909466

1433E
14-3-3 protein epsilon

1

4

Small-scale

0.618

High

981859

RON
Macrophage-stimulating protein receptor

1

20

Small-scale

0.618

High

981860

1433F
14-3-3 protein eta

1

20

Small-scale

0.618

High

981895

SYNE1
Nesprin-1

1

20

High-throughput

0.618

High

981901

TITIN
Titin

1

8

High-throughput

0.618

High

981924

WNK1
Serine/threonine-protein kinase WNK1

1

20

High-throughput

0.618

High

905845

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

6

Small-scale

0.578

High

981933

CHIP
E3 ubiquitin-protein ligase CHIP

1

11

Small-scale

0.561

High

981890

LRC49
Leucine-rich repeat-containing protein 49

1

20

High-throughput

0.553

High

981868

PTC1
Protein patched homolog 1

1

4

High-throughput

0.536

High

981902

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.536

High

981909

T106A
Transmembrane protein 106A

1

9

High-throughput

0.536

High

981910

ASIC4
Acid-sensing ion channel 4

1

4

High-throughput

0.536

High

126799

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

434828

CXB1
Gap junction beta-1 protein

1

19

Small-scale

0.501

High

456856

FURIN
Furin

1

3

Small-scale

0.501

High

180122

SIA8E
Alpha-2,8-sialyltransferase 8E

1

6

High-throughput

0.489

High

509642

UBL4A
Ubiquitin-like protein 4A

1

9

High-throughput

0.489

High

514371

PSPC
Surfactant protein C

1

8

High-throughput

0.489

High

532933

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.489

High

803500

BAG6
Large proline-rich protein BAG6

1

18

High-throughput

0.489

High

981879

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.489

High

981886

BRID5
BRICHOS domain-containing protein 5

1

8

High-throughput

0.489

High

981921

KLK15
Kallikrein-15

1

20

High-throughput

0.489

High

981926

SDF2L
Stromal cell-derived factor 2-like protein 1

1

10

High-throughput

0.489

High

205300

TGON2
Trans-Golgi network integral membrane protein 2

1

20

High-throughput

0.479

High

229373

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

3

High-throughput

0.479

High

230739

AQR
RNA helicase aquarius

1

1

High-throughput

0.479

High

263601

PR40A
Pre-mRNA-processing factor 40 homolog A

1

14

High-throughput

0.479

High

309304

KIF4A
Chromosome-associated kinesin KIF4A

1

5

High-throughput

0.479

High

418943

TPM3
Tropomyosin alpha-3 chain

1

2

High-throughput

0.479

High

423211

PDIA1
Protein disulfide-isomerase

1

20

High-throughput

0.479

High

430933

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

4

High-throughput

0.479

High

431764

HS90A
Heat shock protein HSP 90-alpha

1

20

Small-scale

0.479

High

455350

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.479

High

503944

HSP7C
Heat shock cognate 71 kDa protein

1

11

Small-scale

0.479

High

531803

PDIA4
Protein disulfide-isomerase A4

1

20

High-throughput

0.479

High

538204

ENPL
Endoplasmin

1

20

High-throughput

0.479

High

574657

ARF4
ADP-ribosylation factor 4

1

20

High-throughput

0.479

High

575728

VINC
Vinculin

1

16

High-throughput

0.479

High

670596

ERP29
Endoplasmic reticulum resident protein 29

1

20

High-throughput

0.479

High

671792

PDIA3
Protein disulfide-isomerase A3

1

20

High-throughput

0.479

High

737757

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

Small-scale

0.479

High

788184

CASP3
Caspase-3

1

1

High-throughput

0.479

High

801097

KI67
Proliferation marker protein Ki-67

1

13

High-throughput

0.479

High

802070

NOP2
Probable 28S rRNA

1

9

High-throughput

0.479

High

920943

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

12

High-throughput

0.479

High

931994

TPM4
Tropomyosin alpha-4 chain

1

2

High-throughput

0.479

High

944196

PRKDC
DNA-dependent protein kinase catalytic subunit

1

12

High-throughput

0.479

High

981861

CALD1
Caldesmon

1

20

High-throughput

0.479

High

981864

CKAP4
Cytoskeleton-associated protein 4

1

19

High-throughput

0.479

High

981866

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

2

High-throughput

0.479

High

981872

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

10

High-throughput

0.479

High

981873

SMC1A
Structural maintenance of chromosomes protein 1A

1

15

High-throughput

0.479

High

981877

SYK
Lysine--tRNA ligase

1

8

High-throughput

0.479

High

981888

DHX29
ATP-dependent RNA helicase DHX29

1

5

High-throughput

0.479

High

981889

LYRIC
Protein LYRIC

1

2

High-throughput

0.479

High

981891

DYH10
Dynein axonemal heavy chain 10

1

10

High-throughput

0.479

High

981903

DDX1
ATP-dependent RNA helicase DDX1

1

2

High-throughput

0.479

High

981907

RAD50
DNA repair protein RAD50

1

20

High-throughput

0.479

High

981925

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

1

High-throughput

0.479

High

981928

VAPA
Vesicle-associated membrane protein-associated protein A

1

13

High-throughput

0.479

High

981932

COR1C
Coronin-1C

1

3

High-throughput

0.479

High

981934

CSN3
COP9 signalosome complex subunit 3

1

2

High-throughput

0.479

High

981936

SMC3
Structural maintenance of chromosomes protein 3

1

12

High-throughput

0.479

High

981938

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.479

High

604146

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.458

High

796733

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

806830

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.458

High

981881

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

0

High-throughput

0.458

High

981884

HGNAT
Heparan-alpha-glucosaminide N-acetyltransferase

1

0

High-throughput

0.458

High

981887

GLPK5
Putative glycerol kinase 5

1

0

High-throughput

0.458

High

981897

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.458

High

981920

PDIP3
Polymerase delta-interacting protein 3

1

5

High-throughput

0.457

High

354945

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

20

High-throughput

0.445

High

49013

SHOT1
Shootin-1

1

1

High-throughput

0.437

High

69781

WDR64
WD repeat-containing protein 64

1

4

High-throughput

0.437

High

81964

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

7

High-throughput

0.437

High

150955

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.437

High

981870

BOP1
Ribosome biogenesis protein BOP1

1

3

High-throughput

0.437

High

981871

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

16

High-throughput

0.437

High

981874

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

13

High-throughput

0.437

High

981875

LBR
Delta(14)-sterol reductase LBR

1

2

High-throughput

0.437

High

981876

CND2
Condensin complex subunit 2

1

2

High-throughput

0.437

High

171612

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.437

High

201587

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

5

High-throughput

0.437

High

273083

SURF6
Surfeit locus protein 6

1

4

High-throughput

0.437

High

281244

RL1D1
Ribosomal L1 domain-containing protein 1

1

2

High-throughput

0.437

High

330558

ZBED1
E3 SUMO-protein ligase ZBED1

1

1

High-throughput

0.437

High

398692

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

6

High-throughput

0.437

High

595871

ICAL
Calpastatin

1

4

High-throughput

0.437

High

704260

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

1

High-throughput

0.437

High

722388

RL22
Large ribosomal subunit protein eL22

1

2

High-throughput

0.437

High

805644

RL27A
Large ribosomal subunit protein uL15

1

1

High-throughput

0.437

High

806291

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.437

High

814768

RL29
Large ribosomal subunit protein eL29

1

2

High-throughput

0.437

High

825171

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.437

High

825396

LMAN1
Protein ERGIC-53

1

6

High-throughput

0.437

High

839574

SERPH
Serpin H1

1

8

High-throughput

0.437

High

898888

PSME3
Proteasome activator complex subunit 3

1

2

High-throughput

0.437

High

922978

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.437

High

951523

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.437

High

981863

EXOS9
Exosome complex component RRP45

1

3

High-throughput

0.437

High

981865

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

9

High-throughput

0.437

High

981869

NOG2
Nucleolar GTP-binding protein 2

1

6

High-throughput

0.437

High

981882

GLE1
mRNA export factor GLE1

1

6

High-throughput

0.437

High

981892

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

16

High-throughput

0.437

High

981893

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

2

High-throughput

0.437

High

981894

TXND5
Thioredoxin domain-containing protein 5

1

20

High-throughput

0.437

High

981896

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

12

High-throughput

0.437

High

981898

BRX1
Ribosome biogenesis protein BRX1 homolog

1

6

High-throughput

0.437

High

981899

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.437

High

981904

H1X
Histone H1.10

1

1

High-throughput

0.437

High

981905

GCN1
Stalled ribosome sensor GCN1

1

13

High-throughput

0.437

High

981906

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.437

High

981908

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

20

High-throughput

0.437

High

981912

ZN512
Zinc finger protein 512

1

8

High-throughput

0.437

High

981914

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.437

High

981917

NP1L4
Nucleosome assembly protein 1-like 4

1

2

High-throughput

0.437

High

981918

EBP2
Probable rRNA-processing protein EBP2

1

2

High-throughput

0.437

High

981919

GNL3
Guanine nucleotide-binding protein-like 3

1

6

High-throughput

0.437

High

981922

TMX1
Thioredoxin-related transmembrane protein 1

1

20

High-throughput

0.437

High

981923

UN45A
Protein unc-45 homolog A

1

13

High-throughput

0.437

High

981927

FBX6
F-box only protein 6

1

20

High-throughput

0.437

High

981935

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

981937

SF3B6
Splicing factor 3B subunit 6

1

5

High-throughput

0.437

High

981939

COPG1
Coatomer subunit gamma-1

1

11

High-throughput

0.437

High

981940

TACC3
Transforming acidic coiled-coil-containing protein 3

1

12

High-throughput

0.437

High

981941

PCLO
Protein piccolo

1

10

High-throughput

0.437

High

968821

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

283500

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

456112

DPOLA
DNA polymerase alpha catalytic subunit

1

0

High-throughput

0.249

Low

739699

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.249

Low

790371

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.249

Low

812996

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.249

Low

901657

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.249

Low

911352

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.249

Low

921826

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

949449

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.249

Low

981862

EMAL5
Echinoderm microtubule-associated protein-like 5

1

0

High-throughput

0.249

Low

981880

TBR1
T-box brain protein 1

1

0

High-throughput

0.249

Low

981883

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.249

Low

981885

H3C
Histone H3.3C

1

0

High-throughput

0.249

Low

981900

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.249

Low

981911

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.249

Low

981913

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

981915

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.249

Low

981916

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.249

Low

981929

UXT
Protein UXT

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024