HitPredict

Interactor 1: CPSF1 (Q10570)
Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)
Gene: CPSF1

Interactor 2: WDR33 (Q9C0J8)
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa)
Gene: WDR33

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.860

The method score is based on:

Property Details
Experiments 29274231, 29395067, 24981860, 35177536
Identification Methods x-ray crystallography, proximity labelling technology, affinity chromatography technology, pull down
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~WD40, MMS1_N~WD40
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1443
Hs

1 1336
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024